SBB-Analogue (GL13) Biotin
Based on 1 publication(s) in Google Scholar
SBB-Analogue (GL13) Biotin (GL13; SBB-A-B) consists of a Sudan Black B (SBB) (HY-D0213) derivative conjugated with biotin. SBB-Analogue (GL13) Biotin potently detects senescent cells and eliminates the drawback of false-positive staining caused by serum starvation and cell fusion in SA-β-gal assays. SBB-Analogue (GL13) Biotin can be used in flow cytometry, immunofluorescence analysis, and other applications.
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.30%
- CAS 番号: 2171036-89-6
- 分子式: C39H38N8O3S
- 分子量:698.84
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
MedChemExpress（MCE）の使用を引用している文献 SBB-Analogue (GL13) Biotin
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生物活性
SBB-Analogue (GL13) Biotin specifically stains and detects lipofuscin-containing senescent cells, including U2OS hCdt1 Tet-ON, human diploid lung fibroblasts, HBEC-Cdc6 Tet-ON, and irradiated Saos2-p21WAF1/Cip1 cells. It exhibits higher sensitivity, lower background, and complete consistency with established senescence markers[1].
SBB-Analogue (GL13) Biotin stains perinuclear structures or cytoplasmic granules in senescent cells; when used with an avidin-peroxidase conjugated detection system, it produces a clear insoluble product, thereby enhancing visualization[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2171036-89-6
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性状 Solid
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分子量 698.84
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分子式 C39H38N8O3S
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Color Brown to black
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SMILES
O=C(N1)N[C@](CS2)([H])[C@@]1([H])[C@@H]2CCCCC(OCC(C)(N3)NC4=CC=C(C5=C4C3=CC=C5)/N=N/C6=CC=C(/N=N/C7=CC=CC=C7)C8=C6C=CC=C8)=O
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別名
GL13; SBB-A-B
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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Adv Sci (Weinh)
2025 Oct 5:e04474. PMID: 41047496
純度とドキュメンテーション
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データシート (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
SBB-Analogue (GL13) Biotin 関連分類
HY-158742 関連分類
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