SBB-Analogue (GL13) Biotin
Based on 1 publication(s) in Google Scholar
SBB-Analogue (GL13) Biotin (GL13; SBB-A-B) consists of a Sudan Black B (SBB) (HY-D0213) derivative conjugated with biotin. SBB-Analogue (GL13) Biotin potently detects senescent cells and eliminates the drawback of false-positive staining caused by serum starvation and cell fusion in SA-β-gal assays. SBB-Analogue (GL13) Biotin can be used in flow cytometry, immunofluorescence analysis, and other applications.
For research use only. We do not sell to patients.
- Purity: 99.30%
- CAS No.: 2171036-89-6
- Formula: C39H38N8O3S
- Molecular Weight:698.84
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
Publications Citing Use of MedChemExpress (MCE) SBB-Analogue (GL13) Biotin
More
Biological Activity
SBB-Analogue (GL13) Biotin specifically stains and detects lipofuscin-containing senescent cells, including U2OS hCdt1 Tet-ON, human diploid lung fibroblasts, HBEC-Cdc6 Tet-ON, and irradiated Saos2-p21WAF1/Cip1 cells. It exhibits higher sensitivity, lower background, and complete consistency with established senescence markers[1].
SBB-Analogue (GL13) Biotin stains perinuclear structures or cytoplasmic granules in senescent cells; when used with an avidin-peroxidase conjugated detection system, it produces a clear insoluble product, thereby enhancing visualization[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 2171036-89-6
-
Appearance Solid
-
Molecular Weight 698.84
-
Formula C39H38N8O3S
-
Color Brown to black
-
SMILES
O=C(N1)N[C@](CS2)([H])[C@@]1([H])[C@@H]2CCCCC(OCC(C)(N3)NC4=CC=C(C5=C4C3=CC=C5)/N=N/C6=CC=C(/N=N/C7=CC=CC=C7)C8=C6C=CC=C8)=O
-
Synonyms
GL13; SBB-A-B
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
-
Journal Impact Factor
-
Most Recent
-
Adv Sci (Weinh)
2025 Oct 5:e04474. PMID: 41047496
Purity & Documentation
-
Data Sheet (268 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SBB-Analogue (GL13) Biotin Related Classifications
HY-158742 Related Classifications
Powered by Bioz