PtdIns-(3,4,5)-P3-biotin sodium
Based on 1 Customer Validation
PtdIns-(3,4,5)-P3-biotin sodium is a Biotin-labeled PtdIns-(3,4,5)-P3 (PI(3,4,5)P3). PI(3,4,5)P3 is a substrate of nuclear phosphatidylinositol 5-phosphatase (PIP5Pase). PI(3,4,5)P3 binds to the N-terminus of RAP1 (repressor activator protein 1) and controls its DNA binding activity.
For research use only. We do not sell to patients.
- Purity : 98.0%
- CAS No.: 1415684-80-8
- Formula: C35H61N3Na4O24P4S
- Molecular Weight:1155.78
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
- Purity & Documentation
- References
-
Help & FAQs
-
HY-148971A
PtdIns-(345)-P3 (12-dipalmitoyl) sodium -
HY-A0183
Phosphatidylserine -
HY-141420
PtdIns-(3,4,5)-P3(1,2-dihexanoyl) ammonium -
HY-W040255
1-Palmitoyl-2-glutaryl-sn-glycero-3-phosphocholine -
HY-131482
PtdIns-(3)-P1(1,2-dioctanoyl) sodium -
HY-139406
1,2-Dioctanoyl-sn-glycero-3-phospho-(1'-myo-inositol-4'-phosphate) ammonium -
HY-W337335
1-Palmitoyl-sn-glycerol 3-phosphate sodium salt -
HY-W854295
Phosphatidylinositol-1,2-dioctanoyl sodium -
HY-137257
Carbamyl-PAF -
HY-W923661
1-Octadecyl lysophosphatidic acid -
HY-130405
PtdIns-(1,2-dipalmitoyl) ammonium -
HY-158572
PtdIns-(4,5)-P2 (1,2-dipalmitoyl) trisodium
Biological Activity
Description
In Vitro
Transient inactivation of PIP5Pase results in the accumulation of nuclear PI(3,4,5)P3, which binds RAP1 and displaces it from expression sites (ESs), activating transcription of silent ESs and variant surface glycoprotein (VSG) switching[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1415684-80-8
-
Appearance Solid
-
Molecular Weight 1155.78
-
Formula C35H61N3Na4O24P4S
-
Color White to off-white
-
SMILES
O=P(O)(O[Na])O[C@H]1[C@@H]([C@H]([C@@H]([C@@H]([C@@H]1OP(O)(O[Na])=O)O)OP(OC[C@@H](COC(CCCCCCCNC(CCCC[C@H]2[C@]3([H])[C@](NC(N3)=O)([H])CS2)=O)=O)OC(CCCCCCC)=O)(O[Na])=O)O)OP(O)(O[Na])=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
-
Data Sheet (267 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
PtdIns-(3,4,5)-P3-biotin sodium Related Classifications
HY-132276 Related Classifications
Powered by Bioz