1-Palmitoyl-sn-glycerol 3-phosphate sodium salt
Based on 1 Customer Validation
Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) sodium salt is a type of phospholipid and a precursor of lipid membranes. 1-Palmitoyl-sn-glycerol 3-phosphate sodium salt can be incorporated into POPC liposomes, resulting in significant changes in membrane curvature. 1-Palmitoyl-sn-glycerol 3-phosphate sodium salt can induce platelet aggregation, but its activity is 30 times lower than that of 1-hexadecyl-sn-glyceryl-3-phosphate.
For research use only. We do not sell to patients.
- Purity : 99.67%
- CAS No.: 17618-08-5
- Formula: C19H38NaO7P
- Molecular Weight:432.46
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Storage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Biological Activity
Description
In Vitro
1-Palmitoyl-sn-glycerol 3-phosphate sodium salt induces aggregation of platelet suspensions, with a half-maximal effective concentration (EC50) of 290 nM[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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CAS No. 17618-08-5
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Appearance Solid
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Molecular Weight 432.46
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Formula C19H38NaO7P
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Color White to off-white
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SMILES
O=P(O)(O[Na])OC[C@H](O)COC(CCCCCCCCCCCCCCC)=O
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Synonyms
1-P-GPA sodium salt
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvent & Solubility
In Vitro:
H2O : 50 mg/mL (115.62 mM; Need ultrasonic)
Methanol : 2.5 mg/mL (5.78 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (267 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
[1]. Wick R, et al. Enzyme-containing liposomes can endogenously produce membrane-constituting lipids. Chem Biol. 1996;3(4):277-285. [Content Brief]
[2]. Simon MF, et al. Human platelet aggregation induced by 1-alkyl-lysophosphatidic acid and its analogs: a new group of phospholipid mediators? Biochem Biophys Res Commun. 1982 Oct 29;108(4):1743-50. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Methanol / H2O | 1 mM | 2.3124 mL | 11.5618 mL | 23.1235 mL | 57.8088 mL |
| 5 mM | 0.4625 mL | 2.3124 mL | 4.6247 mL | 11.5618 mL | |
| H2O | 10 mM | 0.2312 mL | 1.1562 mL | 2.3124 mL | 5.7809 mL |
| 15 mM | 0.1542 mL | 0.7708 mL | 1.5416 mL | 3.8539 mL | |
| 20 mM | 0.1156 mL | 0.5781 mL | 1.1562 mL | 2.8904 mL | |
| 25 mM | 0.0925 mL | 0.4625 mL | 0.9249 mL | 2.3124 mL | |
| 30 mM | 0.0771 mL | 0.3854 mL | 0.7708 mL | 1.9270 mL | |
| 40 mM | 0.0578 mL | 0.2890 mL | 0.5781 mL | 1.4452 mL | |
| 50 mM | 0.0462 mL | 0.2312 mL | 0.4625 mL | 1.1562 mL | |
| 60 mM | 0.0385 mL | 0.1927 mL | 0.3854 mL | 0.9635 mL | |
| 80 mM | 0.0289 mL | 0.1445 mL | 0.2890 mL | 0.7226 mL | |
| 100 mM | 0.0231 mL | 0.1156 mL | 0.2312 mL | 0.5781 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.