17618-08-5
17618-08-5
Chemical Structure
1-Palmitoyl-sn-glycerol 3-phosphate sodium salt
Synonym(s): 1-P-GPA sodium salt
- CAS No.: 17618-08-5
- Formula:C19H38NaO7P
- Molecular Weight:432.46
IUPAC Name: 4-(3-bromopropoxy)benzaldehyde
InChIKey: NWOPIWLNGYLZCJ-GMUIIQOCSA-M
SMILES: O=P(O)(O[Na])OC[C@H](O)COC(CCCCCCCCCCCCCCC)=O
Biological Activity: Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) sodium salt is a type of phospholipid and a precursor of lipid membranes. 1-Palmitoyl-sn-glycerol 3-phosphate sodium salt can be incorporated into POPC liposomes, resulting in significant changes in membrane curvature. 1-Palmitoyl-sn-glycerol 3-phosphate sodium salt can induce platelet aggregation, but its activity is 30 times lower than that of 1-hexadecyl-sn-glyceryl-3-phosphate[1][2].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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1-Palmitoyl-sn-glycerol 3-phosphate sodium salt | 99.67% | Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) sodium salt is a type of phospholipid and a precursor of lipid membranes. 1-Palmitoyl-sn-glycerol 3-phosphate sodium salt can be incorporated into POPC liposomes, resulting in significant changes in membrane curvature. 1-Palmitoyl-sn-glycerol 3-phosphate sodium salt can induce platelet aggregation, but its activity is 30 times lower than that of 1-hexadecyl-sn-glyceryl-3-phosphate. | ||||||||||||||||||||
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1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate-13C16 sodium | 1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate-13C16 (sodium) is 13C16 labeled 1-Palmitoyl-2-hydroxy-sn-glycero-3-phosphate. | |||||||||||||||||||||
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(Rac)-1-Oleoyl lysophosphatidic acid sodium | 98% | (Rac)-1-Oleoyl lysophosphatidic acid ((Rac)-1-Oleoyl-sn-glycero-3-phosphate) sodium is the racemic isomer of 1-Oleoyl lysophosphatidic acid sodium (HY-107614). | ||||||||||||||||||||
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1-Oleoyl lysophosphatidic acid sodium (GMP) | 1-Oleoyl lysophosphatidic acid sodium (GMP) is the GMP-grade form of 1-Oleoyl lysophosphatidic acid sodium (HY-107614). GMP-grade small molecules serve as auxiliary reagents in cell therapy. 1-Oleoyl lysophosphatidic acid sodium is a bioactive lipid signaling molecule. 1-Oleoyl lysophosphatidic acid sodium inhibits lysoPLD-catalyzed hydrolysis of lysophosphatidylcholine and FS-3. 1-Oleoyl lysophosphatidic acid sodium activates LPA1 and LPA2, thereby triggering calcium mobilization, NFATc1 translocation, Rho/ROCK activation, Smad2/3 phosphorylation and c-Fos expression. 1-Oleoyl lysophosphatidic acid sodium induces anxiety-like, depression-like and hypoactivity phenotypes, regulates osteoclast cytoskeleton and viability, reduces osteoclast bone resorptive activity, and drives mesenchymal stem cell differentiation into myofibroblast-like cells. 1-Oleoyl lysophosphatidic acid sodium stimulates the secretion of transforming growth factor-β1 and stromal cell-derived factor-1. 1-Oleoyl lysophosphatidic acid sodium is applicable to research related to anxiety, depression and ovarian cancer. | |||||||||||||||||||||
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1-Palmitoyl-sn-glycerol 3-phosphate | 98.3% | 1-Palmitoyl-sn-glycerol 3-phosphate (1-P-GPA) is a phospholipid and lipid membrane precursor. 1-Palmitoyl-sn-glycerol 3-phosphate integrates into POPC liposomes, causing significant changes in membrane curvature. 1-Palmitoyl-sn-glycerol 3-phosphate induces platelet aggregation, but its activity is 30-fold lower than that of 1-hexadecyl-sn-glyceryl-3-phosphate. | ||||||||||||||||||||
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1-Palmitoyl-2-hydroxy-sn-glycero-3-PE | 99.9% | 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid. 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE also acts as an immune response regulator and toxicity alleviator produced by Microcystis aeruginosa under Cu2+ stress. | ||||||||||||||||||||
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1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) sodium | 99.0% | 1-Palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (16:0 Lyso PE) sodium is a lysophospholipid containing palmitic acid (16:0) at the sn-1 position. It can be used in the generation of micelles, liposomes, and other types of artificial membranes, including lipid-based drug carrier systems. | ||||||||||||||||||||
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1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine | 99.1% | 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine (14:0 Lyso PE) is a lysophospholipid with a phosphoethanolamine head and a myristoyl tail. The free amine group can conjugate with NHS active ester or coupled with carboxylic acid in the presence of a coupling agent. It also induces transient increases in intracellular calcium in PC12 cells . Serum levels of 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphoethanolamine are elevated in patients with malignant breast cancer compared to healthy controls. | ||||||||||||||||||||
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1-Myristoyl-2-hydroxy-sn-glycero-3-phosphate sodium | 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphate sodium is a kind of activity that promotes platelet aggregation and stimulates smooth muscle contraction. 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphate sodium can enhance cell chemotaxis and cytoskeletal rearrangement. 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphate sodium can also promote Ca2+ mobilization and neurotransmitter release. 1-Myristoyl-2-hydroxy-sn-glycero-3-phosphate sodium also has a certain effect on cell proliferation. | |||||||||||||||||||||
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1-Stearoyl-sn-glycerol 3-phosphate sodium | 98.21% | 1-Stearoyl-sn-glycerol 3-phosphate sodium is a bioactive phospholipid that plays a crucial role in modulating cellular processes such as motility, proliferation, invasion, survival, and growth factor production, primarily through its interaction with G protein-coupled receptors (GPCRs). Typically found at low concentrations in plasma (~100nM), this compound is synthesized during the formation of membrane phospholipids and is derived from various cell types, including activated platelets, epithelial cells, leukocytes, neuronal cells, and tumor cells. Its unique structure includes stearic acid at the sn-1 position alongside a hydroxyl group at the sn-2 position. | ||||||||||||||||||||
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17:0 Lyso PA sodium | 17:0 Lyso PA sodium is a lysophosphatidic acid. | |||||||||||||||||||||
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References
- [1]. Wick R, et al. Enzyme-containing liposomes can endogenously produce membrane-constituting lipids. Chem Biol. 1996;3(4):277-285. [Content Brief]
- [2]. Simon MF, et al. Human platelet aggregation induced by 1-alkyl-lysophosphatidic acid and its analogs: a new group of phospholipid mediators? Biochem Biophys Res Commun. 1982 Oct 29;108(4):1743-50. [Content Brief]
