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tri-GalNAc biotin 

Cat. No.: HY-147102
Handling Instructions

tri-GalNAc biotin is a small molecule lysosome targeting degrader. tri-GalNAc is a ligand of ASGPR (asialoglycoprotein receptor). tri-GalNAc biotin can facilitate the uptake of NeutrAvidin (NA) through ASGPR in liver cells. tri-GalNAc biotin delivers NeutrAvidin to lysosome for degradation. tri-GalNAc biotin can be used for research of LYsosome TArgeting Chimera (LYTAC).

For research use only. We do not sell to patients.

tri-GalNAc biotin Chemical Structure

tri-GalNAc biotin Chemical Structure

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Description

tri-GalNAc biotin is a small molecule lysosome targeting degrader. tri-GalNAc is a ligand of ASGPR (asialoglycoprotein receptor). tri-GalNAc biotin can facilitate the uptake of NeutrAvidin (NA) through ASGPR in liver cells. tri-GalNAc biotin delivers NeutrAvidin to lysosome for degradation. tri-GalNAc biotin can be used for research of LYsosome TArgeting Chimera (LYTAC)[1].

Molecular Weight

1916.19

Formula

C83H146N14O34S

SMILES

O=C(CCNC(CCOCCOCCOCCNC(CCCC[[email protected]@H]1SC[[email protected]]([[email protected]]1([H])N2)([H])NC2=O)=O)=O)NC(COCCC(NCCCNC(CCCCO[[email protected]](O[[email protected]@H]3CO)[[email protected]@H]([[email protected]]([[email protected]]3O)O)NC(C)=O)=O)=O)(COCCC(NCCCNC(CCCCO[[email protected]](O[[email protected]@H]4CO)[[email protected]@H]([[email protected]]([[email protected]]4O)O)NC(C)=O)=O)=O)COCCC(NCCCNC(CCCCO[[email protected]](O[[email protected]@H]5CO)[[email protected]@H]([[email protected]]([[email protected]]5O)O)NC(C)=O)=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
tri-GalNAc biotin
Cat. No.:
HY-147102
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