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Results for "

Beta+catenin

" in MedChemExpress (MCE) Product Catalog:

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研究分野別:	Cancer (286) Cardiovascular Disease (19) Endocrinology (15) Infection (24) Inflammation/Immunology (75) Metabolic Disease (56) Neurological Disease (63)
Oligonucleotides:	siRNA drugs (2) siRNAs (2)

381

阻害剤およびアゴニスト

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蛍光色素

生化学アッセイ試薬

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IWR-1 60+ Cited Publications endo-IWR 1; IWR-1-endo	Organoid Wnt	Inflammation/Immunology Cancer
IWR-1 (IWR-1-endo) is a tankyrase inhibitor targeting *Wnt/β-catenin* (IC₅₀ = 180 nM). IWR-1 compromises critical steps of the canonical Wnt signaling, namely translocation of β-catenin to the nucleus and subsequent TCF/LEF activation and expression of Wnt/β-catenin downstream targets. IWR-1 promotes β-catenin phosphorylation by promoting stability of Axin-scaffolded destruction complexes. IWR-1 can be studied in research for anti-tumor purposes, and diseases such as osteosarcoma, colorectal cancer and psoriasis .

ICG-001 60+ Cited Publications	β-catenin Apoptosis	Cancer
ICG-001 is an inhibitor of *β-catenin/TCF* mediated transcription. ICG-001 works by specifically binding to cyclic AMP response element-binding protein with an IC₅₀ of 3 μM. ICG-001 selectively blocks the β-catenin/CBP interaction without interfering with the β-catenin/p300 interaction.

MSAB 45+ Cited Publications	Wnt β-catenin	Cancer
MSAB is a potent and selective inhibitor of *Wnt/β-catenin* signaling. MSAB binds to β-catenin and promotes its degradation, and specifically downregulates Wnt/β-catenin target genes. MSAB exhibits potent anti-tumor effects selectively on Wnt-dependent cancer cells .

SKL2001 60+ Cited Publications	Wnt β-catenin	Cancer
SKL2001 is an agonist of the *Wnt/β-catenin* pathway, with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction .

TWS119 30+ Cited Publications	Wnt GSK-3 Autophagy	Neurological Disease Cancer
TWS119 is an inhibitor of *GSK-3β, with an IC₅₀* of 30 nM, and activates the wnt/β-catenin pathway.

Neohesperidin 5+ Cited Publications Hesperetin 7-O-neohesperidoside	β-catenin Wnt	Inflammation/Immunology
Neohesperidin is a flavonoid compound abundant in citrus plants with antioxidant and anti-inflammatory effects. Neohesperidin can upregulate the *Wnt/β-catenin* signaling pathway, enhance the nuclear translocation of β-catenin and the differentiation of bone marrow stromal cells .

Foscenvivint 1 Publications Verification PRI-724	Wnt	Cancer
PRI-724 is a selective inhibitor of the *CBP/β-catenin* interaction.

Tegatrabetan 5 Publications Verification Tegavivint; BC2059	β-catenin	Cancer
Tegatrabetan (BC2059) is a *β-Catenin* antagonist. Tegatrabetan disrupts the binding of β-catenin with the scaffold protein transducin β-like 1 (TBL1) .

iCRT3 10+ Cited Publications	Wnt Apoptosis	Cancer
iCRT3 is an inhibitor of both Wnt and β-catenin-responsive transcription.

E-7386	Epigenetic Reader Domain	Cancer
E-7386 is an orally active *CBP/beta-catenin* modulator.

FH535 15+ Cited Publications	PPAR Wnt β-catenin	Cancer
FH535 is an inhibitor of *Wnt/β-catenin* and PPAR with anti-tumor activities .

PNU-74654 10+ Cited Publications	Wnt β-catenin Apoptosis	Cancer
PNU-74654 is an inhibitor of *Wnt/β-catenin* pathway with an IC₅₀ of 129.8 μM in NCI-H295 cell.

WIKI4 4 Publications Verification	PARP β-catenin Wnt	Cancer
WIKI4 is a potent tankyrase inhibitor with an IC₅₀ of 26 nM for TNKS2. WIKI4 potently inhibits *Wnt/β-catenin* signaling and that its half-maximal response dose is 75 nM. WIKI4 mediates its effects on *Wnt/β-catenin* signaling by inhibiting the enzymatic activity of TNKS2 . WIKI4 is cytotoxic to SCLC cells with an IC₅₀ value of 0.02 μM .

*Wnt/β-catenin* agonist 4**	Wnt	Cancer
Wnt/β-catenin agonist 4 (Derivative 83) is an agonist of Wnt that activates *Wnt/β-catenin* signal transmission .

xStAx-VHLL 3 Publications Verification	Wnt PROTACs β-catenin	Cancer
xStAx-VHLL is a β-catenin PROTAC degrader that promotes ubiquitination and proteasome degradation of *β-catenin. xStAx-VHLL inhibits the Wnt/β-catenin* signaling pathway. xStAx-VHLL can inhibit the proliferation of colon cancer cells and has anti-tumor activity .

UU-T01	β-catenin	Cancer
UU-T01 is a *β-catenin* inhibitor with a K_D of 0.531 μM. UU-T01 binds to the K435, R469 and K508 residues of β-catenin, disrupting the β-catenin/TCF4 protein-protein interaction .

IQ 1	Wnt	Others
IQ 1 is a *Wnt/β-catenin/CBP* signalling sustainer. IQ 1 maintains long-term expansion of *Wnt/β-catenin*-driven mouse embryonic stem cells (ESCs) and prevents spontaneous differentiation by enhancing *β-catenin/CBP*-mediated transcription and preventing conversion to *β-catenin/p300*-mediated transcription. IQ-1 regulates Wnt signalling by interacting with PR72/130. IQ 1 can be used in study of ESCs expansion .

NRX-252262	Molecular Glues β-catenin E1/E2/E3 Enzyme	Cancer
NRX-252262 is a potent enhancer of the interaction between *β-Catenin, and its cognate E3 ligase, SCF ^β-TrCP, induces mutant β-catenin* degradation, with an EC₅₀ of 3.8 nM .

KYA1797K 15+ Cited Publications	Wnt β-catenin	Cancer
KYA1797K is a potent and selective *Wnt/β-catenin* inhibitor with an IC₅₀ of 0.75 µM.

*Wnt/β-catenin-IN-6*	Wnt β-catenin EGFR ERK COX Akt GSK-3 c-Myc Apoptosis Interleukin Related JNK	Inflammation/Immunology Cancer
Wnt/β-catenin-IN-6 is an orally active *Wnt/β-catenin* pathway inhibitor. Wnt/β-catenin-IN-6 blocks the *AKT/GSK-3β/β-catenin* signaling pathway, leading to reduced expression of Wnt target genes (c-Myc, c-Jun). Wnt/β-catenin-IN-6 reduces COX2 expression and IL-8 levels, highlighting its dual anti-inflammatory and antitumor effects. Wnt/β-catenin-IN-6 can induce apoptosis. Wnt/β-catenin-IN-6 serves as a tool for non-small cell lung cancer (NSCLC) research .

KY1220 3 Publications Verification	Wnt β-catenin	Cancer
KY1220 is a compound that destabilizes both β-catenin and Ras, via targeting the *Wnt/β-catenin* pathway, with an IC₅₀ of 2.1 μM in HEK293 reporter cells .

NRX-252114	Molecular Glues β-catenin	Cancer
NRX-252114 is a potent enhancer of the interaction between *β-catenin, and its cognate E3 ligase, SCF ^β-TrCP. NRX-252114 enhances the binding of pSer33/S37A β-catenin* peptide for β-TrCP with an EC₅₀ of 6.5 nM and a K_d of 0.4 nM. NRX-252114 induces mutant β-catenin degradation .

NRX-2663 1 Publications Verification	β-catenin E1/E2/E3 Enzyme	Cancer
NRX-2663 is an enhancer of the interaction between *β-catenin, and its cognate E3 ligase, SCF ^β-TrCP. NRX-2663 enhances the binding of β-catenin* peptide for β-TrCP with an EC₅₀ of 22.9 μM and a K_d of 54.8 nM .

CWP232228 5+ Cited Publications	β-catenin Wnt	Cancer
CWP232228, a highly potent selective *Wnt/β-catenin* signaling inhibitor, antagonizes binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 suppresses tumor formation and metastasis without toxicity through the inhibition of the growth of breast and liver cancer stem cells (CSCs) .

fStAx-35R TFA	Wnt β-catenin	Cancer
fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits *Wnt/β-catenin* signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .

Miclxin 1 Publications Verification DS37262926	Wnt β-catenin Apoptosis	Cancer
Miclxin (DS37262926) is a potent inhibitor of mutant *β-catenin, involving in Wnt signaling pathway. Miclxin induces β-catenin-dependent apoptosis, leads to severe mitochondrial damage with the loss of mitochondrial membrane. Miclxin kills tumor via targeting to MIC60*, a major components of the mitochondrial contact site and cristae organizing system (MICOS) complex .

NRX-1933	β-catenin Molecular Glues	Cancer
NRX-1933 is a type of molecular glue. NRX-1933 is a *β-catenin*:β-TrCP interaction enhancer for the development of small molecule degraders. NRX-1933 promotes the ubiquitination of mutated β-Catenin, leading to degradation. NRX-1933 can be applied to tumor research on abnormal activation of Wnt/β - catenin signaling pathway .

β-catenin-IN-3 1 Publications Verification	β-catenin Wnt CDK	Cancer
β-catenin-IN-3 (Compound C2) is a selective *β-catenin* inhibitor. β-catenin-IN-3 binds to allosteric site on the surface of β-catenin with K_D calculated at 54.96 nM. β-catenin-IN-3 selectively inhibits β-catenin via targeting a cryptic allosteric modulation site, lowers its cellular load. β-catenin-IN-3 significantly reduces viability of β-catenin driven cancer cells, and triggers β-catenin degradation via proteasome system in β-catenin-overexpressing cancer cells .

β-catenin-IN-2 3 Publications Verification	β-catenin	Cancer
β-catenin-IN-2 (Compound H1B1) is a potent *β-catenin* inhibitor. β-catenin-IN-2 can be used for the study of colorectal cancer .

*Wnt/β-catenin* agonist 3**	Wnt β-catenin	Cardiovascular Disease
Wnt/β-catenin agonist 3 (compound 98) is a *Wnt/β-catenin* signalling pathway agonist. Wnt/β-catenin agonist 3 can be used for the research of osteoporosis .

*Wnt/β-catenin* agonist 2** 1 Publications Verification	Wnt β-catenin	Others
Wnt/β-catenin agonist 2 is a potent Wnt agonist. Wnt/β-catenin agonist 2 activates Wnt/β-catenin signaling and can be used in the research of diseases related to the signal transduction . (From patent WO2007078113A1, compound 39)

*Wnt/β-catenin* agonist 1** 5+ Cited Publications	Wnt	Cancer
Wnt/β-catenin agonist 1 (compound 3f) is a *Wnt/β-catenin* signalling pathway agonist, with an EC₅₀ of 0.27 μM .

Windorphen	Wnt β-catenin Histone Acetyltransferase	Cancer
Windorphen is a *Wnt/β-catenin* signal inhibitor that specifically targets the function of the c-terminal transactivation domain of *β-catenin-1* but not β-catenin-2. Windorphen selectively targets p300, disrupting the association of the mammalian β-catenin with p300 but not CBP .

C-82	β-catenin Wnt	Cancer
C-82 is a second-generation specific *CBP/β-catenin* antagonist, which inhibits the binding between β-catenin and CBP and increases the binding between β-catenin and p300 .

xStAx-VHLL TFA 3 Publications Verification	PROTACs β-catenin Wnt	Cancer
xStAx-VHLL TFA is a β-catenin PROTAC degrader that promotes ubiquitination and proteasome degradation of *β-catenin. xStAx-VHLL TFA inhibits the Wnt/β-catenin* signaling pathway. xStAx-VHLL TFA can inhibit the proliferation of colon cancer cells and has anti-tumor activity .

C-Peptide 1 (rat)	GSK-3 Wnt	Cancer
C-Peptide 1 (rat), a peptide, is aβ-catenin/GSK-3β activator. C-Peptide 1 (rat) can regulate the Wnt/β-catenin signaling pathway. C-Peptide 1 (rat) can be used for the research of cancer .

DK419	Wnt β-catenin c-Myc CDK Survivin	Cancer
DK419 is a potent and orally active *Wnt/β-catenin* signaling inhibitor, with an IC₅₀ of 0.19 μM. DK419 reduces protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin and induces production of pAMPK .

NRX-1532	β-catenin	Cancer
NRX-1532 is a small molecule enhancer of *β-catenin:β-TrCP* interaction.

UU-T02 1 Publications Verification	β-catenin Wnt	Metabolic Disease Cancer
UU-T02 is a novel potent, selective small-molecule inhibitor of β-Catenin/T-cell factor protein-protein interaction *(β-catenin/Tcf PPI)* with a K_i of 1.36 μM . UU-T02 inhibits canonical Wnt signaling and the growth of colorectal cancer cells .

NRX-103095	β-catenin	Cancer
NRX-103095 is an enhancer of the interaction between *β-catenin, and its cognate E3 ligase, SCF ^β-TrCP. NRX-103095 enhances the binding of pSer33/Ser37 β-catenin* peptide for β-TrCP with an EC₅₀ of 163 nM .

NRX-103094	Molecular Glues β-catenin	Cancer
NRX-103094 is a potent enhancer of the interaction between *β-catenin, and its cognate E3 ligase, SCF ^β-TrCP. NRX-103094 enhances the binding of pSer33/Ser37 β-catenin* peptide for β-TrCP with an EC₅₀ of 62 nM and a K_d of 0.6 nM .

*Wnt/β-catenin-IN-2*	Wnt β-catenin	Cancer
Wnt/β-catenin-IN-2 (Compound 3235-0367) is a *Wnt/β-catenin* signaling pathway inhibitor, with IC₅₀ and K_D values of 7.1 and 2.5 μM, respectively. Wnt/β-catenin-IN-2 can be used for the research of cancer .

iCRT-5	Wnt β-catenin	Cancer
iCRT-5 is a β-catenin-regulated transcription (CRT) inhibitor. iCRT-5 can block *Wnt/β-catenin* reporter activity and down regulate β-catenin expression. iCRT-5 can be used for the research of multiple myeloma .

CCT036477	Wnt β-catenin PPAR CDK	Cancer
CCT036477 is a *Wnt/β-catenin* pathway inhibitor. CCT036477 blocks transcription at β-catenin without altering its levels. CCT036477 inhibits proliferation of various cancer cells, development of embryos, and expression of Wnt target genes (PPARδ, Cyclin D1, TCF4, and ID2) .

aStAx-35R TFA	β-catenin Wnt	Cancer
aStAx-35R TFA, a stapled peptide, antagonizes nuclear form of *β-catenin* and inhibits Wnt signaling. aStAx-35R TFA inhibits competitively the binding of β-catenin to TCF4. aStAx-35R TFA selectively induces growth inhibition of Wnt-dependent cancer cells .

β-catenin-IN-4	β-catenin CDK c-Myc	Cancer
β-catenin-IN-4 (Compound 39) is a *β-catenin* inhibitor with a K_i of 0.64 μM. β-catenin-IN-4 reduces the protein expression levels of cyclin D1 and c-Myc .

製品番号	製品名

HY-L201

Cell Proliferation Compound Library

3,398 compounds

Cell proliferation, the increase in cell numbers resulting from cell division, is a complex and tightly regulated process. Cell proliferation is regulated by coordinated entry into the cell cycle, and changes in proliferation are closely linked to disease development. Evolutionary dynamics links tumor growth and progression with cell proliferation, cell death, and mutation rates. In addition, cell proliferation is central to degenerative diseases, the development of which is often accompanied by accelerated multiplication of cancer cells. Therefore, assays of cell proliferation levels are frequently used for laboratory research purposes and increasingly for clinical assessment of tumor aggressiveness and potentially to guide care. It has been shown that multiple key targets are collectively involved in regulating the process of cell proliferation, such as CDK, E2F, pRB, β-Catenin, and others.

MCE collects 3,398 compounds that target and regulate key targets of cell proliferation, which can be used in studies of cell proliferation mechanisms and drug discovery.

HY-L038

Differentiation Inducing Compound Library

2,405 compounds

Stem cells, which are found in all multi-cellular organisms, can divide and differentiate into diverse special cell types and can self-renew to produce more stem cells. To be useful in therapy, stem cells must be converted into desired cell types as necessary which is called induced differentiation or directed differentiation. Understanding and using signaling pathways for differentiation is an important method in successful regenerative medicine. Small molecules or growth factors induce the conversion of stem cells into appropriate progenitor cells, which will later give rise to the desired cell type. There is a variety of signal molecules and molecular families that may affect the establishment of germ layers in vivo, such as fibroblast growth factors (FGFs); the wnt family or superfamily of transforming growth factors β (TGFβ) and bone morphogenetic proteins (BMP). Unfortunately, for now, a high cost of recombinant factors is likely to limit their use on a larger scale in medicine. The more promising technique focuses on the use of small molecules. These small molecules can be used for either activating or deactivating specific signaling pathways. They enhance reprogramming efficiency by creating cells that are compatible with the desired type of tissue. It is a cheaper and non-immunogenic method.

MCE Differentiation Inducing Compound Library contains a unique collection of 2,405 compounds that act on signaling pathways for differentiation. These compounds are potential stimulators for induced differentiation. This library is a useful tool for researching directed differentiation and regenerative medicine.

HY-L020

Wnt/Hedgehog/Notch Compound Library

601 compounds

The developmental proteins Hedgehog, Notch and Wnt are key regulators of cell fate, proliferation, migration and differentiation in several tissues. Their related signaling pathways are frequently activated in tumors, and particularly in the rare subpopulation of cancer stem cells. The Wnt signaling pathway is a conserved pathway in animals. Deregulated Wnt signaling has catastrophic consequences for the developing embryo and it is now well appreciated that defective Wnt signaling is a causative factor for a number of pleiotropic human pathologies, including cancer. Hedgehog signaling pathway is linked to tumorigenesis and is aberrantly activated in a variety of cancers. The Notch signaling pathway is a highly conserved cell signaling system present in most animals. It plays an important role in cell-cell communication, and further regulates embryonic development.

MCE designs a unique collection of 601 Wnt/Hedgehog/Notch signaling pathway-related small molecules. Wnt/Hedgehog/Notch Compound Library serves as a useful tool for stem cell research and anti-cancer drug screening.

HY-L103

Anti-Colorectal Cancer Compound Library

2,491 compounds

Colorectal cancer (CRC), also known as bowel cancer, colon cancer, or rectal cancer, arises as adenocarcinoma from glandular epithelial cells of the large intestine comprised of the colon and rectum. The majority of cases of CRC are sporadic and result from risk factors, such as a sedentary lifestyle, obesity, processed diets, alcohol consumption and smoking. CRC is also a common preventable cancer.

Studies showed several cellular signaling pathways dysregulated in CRC, leading to the onset of malignant phenotypes. Therefore, it is necessary to analyze the signaling pathways involved in the occurrence and development of colorectal cancer to study the progression and drug treatment of colorectal cancer. Among them, Wnt/β-catenin, p53, TGF-β/SMAD, NF-κB, Notch, VEGF and other target genes and signaling pathways are the focus of research. MCE offers a unique collection of 2,491 compounds with identified and potential anti-colorectal cancer activity. MCE anti-colorectal cancer compound library is a useful tool for anti-colorectal cancer drugs screening and other related research.

製品番号	製品名	Type

HY-101085G

SKL2001 (GMP)	蛍光色素
SKL2001 (GMP) is SKL2001 (HY-101085) produced by using GMP guidelines. SKL2001 is an agonist of the *Wnt/β-catenin* pathway, with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction .

HY-12238G

IWR-1

endo-IWR 1; IWR-1-endo

蛍光色素

IWR-1 (IWR-1-endo) (GMP) is the IWR-1 (HY-12238) produced by using GMP guidelines. GMP small molecules work appropriately as an auxiliary reagent for cell therapy manufacture. IWR-1 (IWR-1-endo) is a tankyrase inhibitor targeting Wnt/β-catenin (IC₅₀ = 180 nM). IWR-1 compromises critical steps of the canonical Wnt signaling, namely translocation of β-catenin to the nucleus and subsequent TCF/LEF activation and expression of Wnt/β-catenin downstream targets. IWR-1 promotes β-catenin phosphorylation by promoting stability of Axin-scaffolded destruction complexes. IWR-1 can be studied in research for anti-tumor purposes, and diseases such as osteosarcoma, colorectal cancer and psoriasis .

HY-138794G

XL177A

蛍光色素

XL177A GMP is XL177A (HY-138794) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. XL177A is a covalent USP7 inhibitor that blocks the deubiquitinase activity of USP7. XL177A destabilizes non-canonical PRC1 complexes or KDM6A and reduces chromatin deposition of H2AK119Ub, thereby relieving the repression of neuronal differentiation programs. Meanwhile, XL177A also regulates the ELOF1-UVSSA-USP7-nuclear β-catenin axis, decreasing the transcription levels of related proteins and the accumulation of nuclear β-catenin. XL177A exerts antiviral effects by reducing the expression levels of coronavirus receptors, and exhibits inhibitory activity against APC-mutated colorectal cancer cells, neuroblastoma, and coronaviruses including SARS-CoV-2 variants. XL177A is mainly used in studies related to colorectal cancer, neuroblastoma, and coronavirus infections .

HY-B0356G

Ciprofloxacin

Bay-09867

蛍光色素

Ciprofloxacin GMP is Ciprofloxacin (HY-B0356) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Ciprofloxacin (Bay-09867) is an orally active, blood-brain barrier permeable fluoroquinolone antibacterial agent. Ciprofloxacin exerts bactericidal effects primarily by inhibiting topoisomerase II and IV. Ciprofloxacin inhibits the proliferation of human dental pulp stem cells and chondrocytes from young rats, and also activates the Akt signaling pathway and upregulates markers such as β-catenin and Nanog to maintain the morphological characteristics of stem cells. Ciprofloxacin induces significant neurotoxicity and tissue damage, including reducing serotonin and glutathione levels in the brain, inducing oxidative stress and depression-like behaviors, and causing articular cartilage damage. Ciprofloxacin can be applied to research related to infections of necrotic young permanent teeth and neurotoxicity .

HY-15244G

Alpelisib

蛍光色素

Alpelisib GMP is Alpelisib (HY-15244) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Alpelisib (BYL-719) is an orally active PI3Kα-selective inhibitor that blocks the conversion of PIP2 to PIP3, thereby inhibiting pathways including PI3K/AKT/mTOR, MAPK/ERK, Notch and JAK-STAT. Alpelisib also induces apoptosis, G0/G1 phase arrest and senescence; it significantly inhibits the proliferation, self-renewal, stemness and epithelial-mesenchymal transition (EMT) of tumor cells, reduces cancer stem cell populations and decreases the expression of stem cell markers. Alpelisib not only enhances the sensitivity to Eribulin (HY-13442) and exerts a synergistic effect with Paclitaxel (HY-B0015), but may also induce drug resistance by upregulating the SGK3/GSK3β/β-catenin signaling pathway. Alpelisib can be applied to research related to breast cancer, gastric cancer and lipomas associated with PTEN hamartoma tumor syndrome .

HY-12292G

IM-12

蛍光色素

IM-12 GMP is IM-12 (HY-12292) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. IM-12 is an orally active anti-inflammatory agent that targets and inhibits the NF-κB and STAT3 signaling pathways. IM-12 activates the Wnt signaling pathway and promotes the nuclear translocation of β-catenin by inhibiting GSK3β, while also blocking the tyrosine kinase activity of p210BCR/ABL. IM-12 reduces the levels of IL-6, IL-17, NO, prostaglandin E2, iNOS and COX-2, and induces ER stress, Ca ²⁺ release, autophagy and apoptosis. IM-12 is heat-sensitive and does not induce autophagy in IM-resistant p210BCR/ABL ^T315I mutant cells. IM-12 is also a component of the 5iLA medium used for naive pluripotent stem cell research. IM-12 has been applied in studies related to carrageenan (HY-125474)-induced hind paw edema, TNBS-induced colitis, and acute and chronic myeloid leukemia .

製品番号	製品名	Type

HY-Y1325I

Sodium acetate trihydrate, 99.5%

生化学アッセイ試薬

Sodium acetate trihydrate, 99.5% is a short-chain fatty acid salt with multiple biological activities. Sodium acetate trihydrate, 99.5% serves as a direct precursor of acetyl-CoA, and it extensively affects gene expression by promoting histone acetylation. Sodium acetate trihydrate, 99.5% can activate the p38 MAPK pathway to induce cancer cell apoptosis. Sodium acetate trihydrate, 99.5% can activate the Wnt/β-catenin signaling pathway to stimulate the proliferation and migration of cecal epithelial cells, thereby improving intestinal health. Sodium acetate trihydrate, 99.5% alleviates lead accumulation and oxidative damage by upregulating the testosterone-dependent eNOS/NO/cGMP signaling pathway, as well as activating the Nrf2/HO-1 pathway and its downstream antioxidant enzymes .

HY-108775A

Sodium thiosulfate (99%, water≤1.0%)

Sodium hyposulfite (99%, water≤1.0%)

生化学アッセイ試薬

Sodium thiosulfate is an antioxidant. Sodium thiosulfate inhibits the expression of p-GSK-3β and β-catenin proteins, reduces IL-1β, COX-2, and Iba-1, and inhibits NFκB activation. Sodium thiosulfate promotes angiogenesis, inhibits inflammation, and improves acute lung injury. Sodium thiosulfate also exhibits anti-cancer activity against melanoma. Sodium thiosulfate also exerts renal protective effects. Sodium thiosulfate can be used in the research of osteoarthritis, brain inflammation, cancer (such as breast cancer, melanoma), and kidney disease .

HY-159059

Ganoderma Lucidum/Reishi Extract

生化学アッセイ試薬

Ganoderma Lucidum/Reishi Extract is a Ganoderma lucidum extract. Ganoderma Lucidum/Reishi Extract reduces the expression of c-Myc, BCL-2, BCL-XL, TERT, PDGFB, eIF4G, Survivin, β-catenin, and eIF4E. Ganoderma Lucidum/Reishi Extract downregulates the gene expression of MMP-9. Ganoderma Lucidum/Reishi Extract upregulates the expression of IL8. Ganoderma Lucidum/Reishi Extract is applicable to the research of inflammatory breast cancer. Ganoderma Lucidum is used in the research of various diseases, such as allergy, arthritis, hypertension, neurasthenia, inflammation, and cancer .

HY-101085G

SKL2001 (GMP)	生化学アッセイ試薬
SKL2001 (GMP) is SKL2001 (HY-101085) produced by using GMP guidelines. SKL2001 is an agonist of the *Wnt/β-catenin* pathway, with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction .

HY-12238G

IWR-1

endo-IWR 1; IWR-1-endo

生化学アッセイ試薬

HY-138794G

XL177A

生化学アッセイ試薬

HY-B0356G

Ciprofloxacin

Bay-09867

生化学アッセイ試薬

HY-15244G

Alpelisib

生化学アッセイ試薬

HY-12292G

IM-12

生化学アッセイ試薬

製品番号	製品名	Target	研究分野

HY-P10925

Zolucatetide FOG-001; I-66	β-catenin	Cancer
Zolucatetide (FOG-001;I-66) is a potent *β-catenin* inhibitor with an IC₅₀ of <50 nM. Zolucatetide can inhibits *β-catenin* and T-cell factor (TCF) transcription factor interaction. Zolucatetide inhibits cell proliferation and induces cell cycle arrest in target cells. Zolucatetide exhibits anti-tumor efficacy in mice bearing COLO320DM colon cancer cell (with APC, TP53 mutations) xenografts. Zolucatetide can be used for the study of colon cancer .

HY-P1416

Foxy-5 Maximum Cited Publications 7 Publications Verification	Wnt	Cancer
Foxy-5, a WNT5A agonist, is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family. Foxy-5 triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the migration and invasion of epithelial cancer cells. Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model .

HY-P5819

xStAx-VHLL 3 Publications Verification	Wnt PROTACs β-catenin	Cancer
xStAx-VHLL is a β-catenin PROTAC degrader that promotes ubiquitination and proteasome degradation of *β-catenin. xStAx-VHLL inhibits the Wnt/β-catenin* signaling pathway. xStAx-VHLL can inhibit the proliferation of colon cancer cells and has anti-tumor activity .

HY-P10925A

(Z)-Zolucatetide (Z)-FOG-001; I-67	β-catenin	Cancer
(Z)-Zolucatetide (I-67) is a *β-catenin* inhibitor with IC₅₀ ≤50 nM. (Z)-Zolucatetide's sequence is Ac-PL3-Asp-Npg-B5-Asp-3COOHF-Aib-Ala-Phe-Lys3-PyrS2-3Thi-BztA-GlnR3-Ala-NH₂. (Z)-Zolucatetide can be used for cancer research .

HY-P10392AF

fStAx-35R TFA	Wnt β-catenin	Cancer
fStAx-35R TFA is the hydrocarbon-stapled peptide. fStAx-35R TFA inhibits *Wnt/β-catenin* signaling pathway by disrupting the β-catenin-TCF interaction. fStAx-35R TFA can be used in cancer research .

HY-P10810

QPH-FR	Wnt β-catenin	Cancer
QPH-FR is a LGR5 inhibitor. QPH-FR competitively binds to LGR5 and prevents the formation of the LGR5/RSPO1 complex. QPH-FR promotes RNF43/ZNRF3-mediated ubiquitination of FZD receptors, inhibits the Wnt β-catenin signaling pathway, and reduces the stemness of colorectal cancer cells. QPH-FR is applicable to relevant research on colorectal cancer .

HY-12557

γ-Glutamylvaline γ-Glu-Val	Endogenous Metabolite CaSR Wnt TNF Receptor Interleukin Related PPAR β-catenin	Inflammation/Immunology
γ‑Glutamylvaline (γ-Glu-Val) is a calcium‑sensing receptor (CaSR) agonist. γ‑Glutamylvaline activates CaSR and facilitates its binding to β‑arrestin 2 to modulate inflammatory and metabolic homeostasis signaling. γ‑Glutamylvaline inhibits TNF‑α‑induced IL‑6/MCP‑1 and enhances adiponectin/PPARγ in adipocytes. γ‑Glutamylvaline upregulates Wnt5a, restores *β‑catenin* phosphorylation, and reduces serine‑phosphorylated IRS‑1 in adipocytes. γ-Glutamylvaline can be used for the research of low-grade chronic inflammation .

HY-P5819A

xStAx-VHLL TFA 3 Publications Verification	PROTACs β-catenin Wnt	Cancer
xStAx-VHLL TFA is a β-catenin PROTAC degrader that promotes ubiquitination and proteasome degradation of *β-catenin. xStAx-VHLL TFA inhibits the Wnt/β-catenin* signaling pathway. xStAx-VHLL TFA can inhibit the proliferation of colon cancer cells and has anti-tumor activity .

HY-P4858

C-Peptide 1 (rat)	GSK-3 Wnt	Cancer
C-Peptide 1 (rat), a peptide, is aβ-catenin/GSK-3β activator. C-Peptide 1 (rat) can regulate the Wnt/β-catenin signaling pathway. C-Peptide 1 (rat) can be used for the research of cancer .

HY-P5189A

*His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA*	Endogenous Metabolite Cholinesterase (ChE)	Others
His-D-beta-Nal-Ala-Trp-D-Phe-Lys-NH2 TFA, is a growth hormone releasing peptide, as well as a metabolite of GHRP-1. GHRP-1, or Ala-His-D-beta Nal-Ala-Trp-D-Phe-Lys-NH2, has the effect of promoting the release of growth hormone (GH). GHRP-1 increases GH release and increases [Ca2+]i levels in static monolayer cells of rat pituitary gland, but does not affect cAMP levels .

HY-P1454

Fz7-21 3 Publications Verification Ac-LPSDDLEFWCHVMY-NH2	Wnt	Cancer
Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove. The EC₅₀ values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 impairs the function of FZD7 in Wnt–β-catenin signalling and stem cell function in intestinal organoids .

HY-P1416A

Foxy-5 TFA Maximum Cited Publications 7 Publications Verification	Wnt	Cancer
Foxy-5 TFA, a WNT5A agonist, is a mimicking peptide of WNT5A which is a non-canonical member of the Wnt family. Foxy-5 TFA triggers cytosolic free calcium signaling without affecting β-catenin activation and it impairs the migration and invasion of epithelial cancer cells. Foxy-5 TFA effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model .

HY-P10392B

aStAx-35R TFA	β-catenin Wnt	Cancer
aStAx-35R TFA, a stapled peptide, antagonizes nuclear form of *β-catenin* and inhibits Wnt signaling. aStAx-35R TFA inhibits competitively the binding of β-catenin to TCF4. aStAx-35R TFA selectively induces growth inhibition of Wnt-dependent cancer cells .

HY-P11112

PTD-DBM	β-catenin Wnt	Inflammation/Immunology
PTD-DBM is a competitive peptide that blocks the CXXC5-Dvl interaction and induces the expression of β-catenin, α-SMA, and type I collagen. PTD-DBM has skin wound healing activity .

HY-P1454A

Fz7-21 TFA 3 Publications Verification Ac-LPSDDLEFWCHVMY-NH2 TFA	Wnt	Cancer
Fz7-21 (Ac-LPSDDLEFWCHVMY-NH2) TFA is a potent peptide antagonist of FZD7 receptors , selectively binds to FZD7 CRD subclass and alters the conformation of the CRD and the architecture of its lipid-binding groove. The EC₅₀ values are 58 and 34 nM for human and mouse FZD7 CRD, respectively. Fz7-21 TFA impairs the function of FZD7 in Wnt-β-catenin signalling and stem cell function in intestinal organoids .

HY-P2272

NLS-StAx-h	Wnt β-catenin	Cancer
NLS-StAx-h is a selective, cell permeable, stapled peptide Wnt signaling inhibitor with an IC₅₀ of 1.4 μM. NLS-StAx-h efficiently inhibits β-catenin-transcription factor interactions. NLS-StAx-h shows anti-proliferation of cancer cells .

HY-P2272A

NLS-StAx-h TFA 1 Publications Verification	Wnt β-catenin	Cancer
NLS-StAx-h TFA is a selective, cell permeable, stapled peptide Wnt signaling inhibitor with an IC₅₀ of 1.4 μM. NLS-StAx-h TFA efficiently inhibits β-catenin-transcription factor interactions. NLS-StAx-h TFA shows anti-proliferation of cancer cells .

HY-P11007

β-catenin inhibitory peptoid	β-catenin Wnt Androgen Receptor	Cancer
β-catenin inhibitory peptoid (compound 13) inhibits the *β-catenin:TCF* interaction with an IC₅₀ of 5.44 µM. β-catenin inhibitory peptoid inhibits both Wnt (IC₅₀ of 0.105 µM) and androgen receptor (AR)-signaling (IC₅₀ of 1.02 µM) in prostate cancer cell lines. β-catenin inhibitory peptoid markedly diminishes cell proliferation of prostate cancer cell lines .

HY-P10392

aStAx-35R	β-catenin Wnt	Cancer
aStAx-35R, a stapled peptide, antagonizes nuclear form of *β-catenin* and inhibits Wnt signaling. aStAx-35R inhibits competitively the binding of β-catenin to TCF4. aStAx-35R selectively induces growth inhibition of Wnt-dependent cancer cells .

HY-P6441

KP-6	β-catenin Wnt	Inflammation/Immunology
KP-6, a polypeptide, is a *Wnt/β-catenin* signal inhibitor. KP-6 inhibits TGF-β and blocks rush fibrosis signal path crucial in vivo. KP-6 suppresses Renal tissues damage and renal fibrosis, and reverse the course of disease of chronic kidney disease (CKD) .

HY-P10652

hsBCL9CT-24	Wnt β-catenin	Cancer
hsBCL9CT-24 is a *Wnt/β-catenin* (b-cat) pathway inhibitor with potent anti-tumor effect. hsBCL9CT-24 reactivates anti-cancer immune response suppressed by the oncogenic Wnt pathway and can be utilized for cancer research .

HY-P11346

N-Cadherin mimic peptide	Cadherin	Inflammation/Immunology
N-Cadherin mimic peptide is a N-cadherin agonist. N-Cadherin mimic peptide promotes N-cadherin homodimerization via enhancing β-catenin signaling, inducing early chondrogenesis and cartilage matrix production in mesenchymal stem cells (MSCs). N-Cadherin mimic peptide is promising for research of MSC-based cartilage regeneration .

HY-P1589

β-catenin peptide	β-catenin	Cancer
β-catenin peptide is a 8-aa peptide, and can promote thymocyte positive selection.

HY-107528

FRATtide	β-catenin GSK-3	Cancer
FRATtide is a peptide derived from the GSK-3 binding protein that inhibits the phosphorylation of Axin and *β-catenin. FRATtide inhibits GSK-3* binding to Axin .

HY-P11660

β-catenin-IN-10	β-catenin Wnt Androgen Receptor	Cancer
β-catenin-IN-10 is a *β-catenin:TCF4* interaction inhibitor with an IC₅₀ of 5.44 μM. β-catenin-IN-10 inhibits the Wnt and AR signaling pathways with IC₅₀ values of 0.105 μM and 1.02 μM, respectively. β-catenin-IN-10 suppresses the proliferation of castration-resistant prostate cancer cells. β-catenin-IN-10 is applicable to research related to prostate cancer .

HY-P11597

Getacatetide CY-101	Wnt β-catenin	Cancer
Getacatetide (CY-101) is a peptide-based *Wnt/β-catenin* inhibitor, which can be used for the study of solid tumors .

HY-P11867

UM206_L	Wnt β-catenin	Others
UM206_L is a linear Wnt fragment peptide derived from conserved Wnt3a/Wnt5a sequences, inactive in soluble form but capable of activating canonical *Wnt/β-catenin* signaling when conjugated to magnetic nanoparticles and exposed to a high-gradient, time-varying magnetic field or immobilized on glass surfaces .

HY-P11867A

UM206_C	Wnt β-catenin	Others
UM206_C is a circular Wnt fragment peptide derived from conserved Wnt3a/Wnt5a sequences, inactive in soluble form but capable of activating canonical *Wnt/β-catenin* signaling when conjugated to magnetic nanoparticles and exposed to a high-gradient, time-varying magnetic field or immobilized on glass surfaces .

製品番号	製品名

HY-K6303

Human iPSC/ESC Cardiomyocyte Induction Differentiation Kit

MCE Human iPSC/ESC Cardiomyocyte Induction Differentiation Kit is based on the classical GiWi system. By precisely modulating the Wnt/β-catenin signaling pathway in a temporally controlled manner (sequential activation and inhibition), the kit enables highly efficient directed differentiation of human pluripotent stem cells into cardiomyocytes. It is suitable for cardiac disease modeling, drug cardiotoxicity assessment, and mechanistic studies.

HY-K6301

Human iPSC/ESC Cortical Brain Organoid Induction Differentiation Kit

MCE Human iPSC/ESC Cortical Brain Organoid Induction Differentiation Kit is a standardized culture system specifically designed to recapitulate the developmental processes and functional features of the human cerebral cortex through forebrain ventralization-based signaling regulation. By sequentially activating the Wnt/β-catenin pathway and gradually inhibiting BMP/Smad signaling, this system efficiently drives human pluripotent stem cells (PSC) to differentiate into high-purity glutamatergic neurons (VGLUT1/2⁺ > 85%), while simultaneously promoting the formation of Pax6⁺/BLBP⁺ radial glial cells that establish a biomimetic ventricular-zone–like structure.

製品番号	製品名	Target	研究分野	Image

HY-P990841

Anti-pan-Glypican Antibody (HS20)	Glycoprotein VI	Cancer
Anti-pan-Glypican Antibody (HS20) is a kind of human IgG1 κ human antibody, targeting to human pan-Glypican. Anti-pan-Glypican Antibody (HS20) can neutralize the heparan sulfate (HS) chains on GPC3 thereby disrupting the Wnt3a-GPC3 interactions leading to blockade of the Wnt3a/β-catenin signaling. Anti-pan-Glypican Antibody (HS20) can be used for the research of cancer, such as hepatocellular carcinoma (HCC) .

Species:	Human (5) Mouse (1)
Tag:	His (6) Strep (1) Avi (1) GST (2)
Source:	Sf9 insect cells (2) E. coli (4)

製品番号	Compare	製品名	Species	Source	Image

HY-P704420

	beta-Catenin Protein, Human (His) beta-Catenin; Catenin beta-1; CTNNB; CTNNB1	Human	E. coli
	Beta-Catenin protein is an important component of the canonical Wnt pathway and regulates cellular processes. In the absence of Wnt, it complexes with AXIN1, AXIN2, APC, CSNK1A1, and GSK3B to promote CTNNB1 phosphorylation and degradation. beta-Catenin Protein, Human (His) is the recombinant human-derived beta-Catenin protein, expressed by E. coli, with N-His labeled tag.

HY-P705176

	beta-Catenin Protein, Human (Biotinylated, His-Avi) Catenof beta-1; Beta-catenin; CTNNB1; CTNNB; CTNNB	Human	E. coli

HY-P74381

	beta-Catenin Protein, Mouse (sf9, His-GST) 1 Publications Verification beta-Catenin; Catenin beta-1; CTNNB; CTNNB1	Mouse	Sf9 insect cells
	β-Catenin is a key component of canonical Wnt signaling, which dynamically controls cellular processes. In the absence of Wnt, it forms a complex leading to phosphorylation and degradation. beta-Catenin Protein, Mouse (sf9, His-GST) is the recombinant mouse-derived beta-Catenin protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P74382

	beta-Catenin Protein, Human (sf9, His-GST) 1 Publications Verification beta-Catenin; Catenin beta-1; CTNNB; CTNNB1	Human	Sf9 insect cells
	Beta-Catenin protein is an important component of the canonical Wnt pathway and regulates cellular processes. In the absence of Wnt, it complexes with AXIN1, AXIN2, APC, CSNK1A1, and GSK3B to promote CTNNB1 phosphorylation and degradation. beta-Catenin Protein, Human (sf9, His-GST) is the recombinant human-derived beta-Catenin protein, expressed by Sf9 insect cells , with N-His, N-GST labeled tag.

HY-P703628

	beta-Catenin Protein, Human (His-Strep) Catenin beta-1; Beta-catenin; CTNNB1; CTNNB; CTNNB	Human	E. coli

HY-P705513

	beta-Catenin Protein, Human (780a.a, His)	Human	E. coli

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Product	在庫あり - + カートに追加
Cat. No.
Species
Source
Tag
Accession
Gene ID
Molecular Weight
Purity
Endotoxin Level
Biological Activity
Appearance
Formulation
Storage & Stability
Shipping
Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / 在庫あり - + カートに追加お問い合わせ

Host:	Mouse (7) Rabbit (9)
Reactivity:	Human (16) Rat (14) Mouse (15) Hamster (1)
Application:	IHC-P (8) ICC/IF (7) mIHC (1) IP (6) WB (16) ChIP (1) FC (3) ELISA (6)
Isotype:	IgG, Kappa (1) IgG,Kappa (1) IgG (9) IgG1 (3) IgG2b (2)
Conjugation:	Non-conjugated (16) Biotin (1)
Clonality:	Monoclonal (13) Recombinant (7)
Modification:	Phosphorylated (5) Unmodified (8)

製品番号	Compare	製品名	Application	Reactivity	Image

HY-P84271

	beta Catenin Antibody (YA3968) CTNNB; MRD19; armadillo; Beta-catenin	WB, IHC-P, FC, ELISA	Human, Mouse
	beta Catenin Antibody (YA3968) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to beta Catenin.

HY-P84271A

	beta Catenin Antibody (YA3968)(PBS only) CTNNB; MRD19; armadillo; Beta-catenin	WB, IHC-P, FC, ELISA	Human, Mouse
	beta Catenin Antibody (YA3968) is a Mouse-derived and non-conjugated IgG2b monoclonal antibody, targeting to beta Catenin.

HY-P81261

	beta Catenin Antibody (YA936) 1 Publications Verification CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin	WB, IHC-P	Human, Mouse, Rat
	beta Catenin Antibody (YA936) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to beta Catenin.

HY-P81261B

	beta Catenin Antibody (YA938) CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin	WB, IHC-P, IP	Human, Mouse, Rat, Hamster
	beta Catenin Antibody (YA938) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to beta Catenin.

HY-P81261A

	beta Catenin Antibody (YA937) CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin	WB	Human, Mouse, Rat
	beta Catenin Antibody (YA937) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to beta Catenin.

HY-P81261AA

	beta Catenin Antibody (YA937)(PBS only) CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin	WB	Human, Mouse, Rat
	beta Catenin Antibody (YA937) is a Mouse-derived and non-conjugated IgG1 monoclonal antibody, targeting to beta Catenin.

HY-P86087

	*Phospho-beta Catenin(Ser675) Antibody (YA5779)* CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Phospho-beta Catenin(Ser675) Antibody (YA5779) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-beta Catenin(Ser675).

HY-P89417

	*Phospho-beta Catenin(Ser552) Antibody (YA8860)* CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin	WB, IHC-P, ICC/IF, FC	Human, Mouse, Rat
	Phospho-beta Catenin(Ser552) Antibody (YA8860) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-beta Catenin(Ser552) .

HY-P83351

	*Phospho-beta Catenin* (Ser33/Ser37) Antibody (YA3096)** CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin	WB	Human, Rat
	Phospho-beta Catenin (Ser33/Ser37) Antibody (YA3096) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-beta Catenin (Ser33/Ser37).

HY-P86248

	*Phospho-beta Catenin(Thr41/Ser45) Antibody (YA5940)* CTNNB1; CTNNB; OK/SW-cl.35; Catenin beta-1; Beta-catenin	WB, ICC/IF, IP, ELISA	Human, Mouse, Rat
	Phospho-beta Catenin(Thr41/Ser45) Antibody (YA5940) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to Phospho-beta Catenin(Thr41/Ser45).

HY-P86730

	beta Catenin Antibody (YA6422) CTNB1_HUMAN; Catenin beta-1; catenin beta 1; CTNNB1; Catenin beta; Beta-catenin; CTNNB; OK/SW-cl.35; PRO2286; EVR7; MRD19; NEDSDV; armadillo; βcatenin; β catenin; β-catenin;	WB	Human, Mouse, Rat
	beta Catenin Antibody (YA6422) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to beta Catenin.

HY-P86730A

	beta Catenin Antibody (YA6422)(PBS only) CTNB1_HUMAN; Catenin beta-1; catenin beta 1; CTNNB1; Catenin beta; Beta-catenin; CTNNB; OK/SW-cl.35; PRO2286; EVR7; MRD19; NEDSDV; armadillo; βcatenin; β catenin; β-catenin;	WB	Human, Mouse, Rat
	beta Catenin Antibody (YA6422) is a Mouse-derived and non-conjugated IgG monoclonal antibody, targeting to beta Catenin.

HY-P80488

	beta Catenin Antibody (YA584) 1 Publications Verification	WB, IHC-P, ICC/IF, IP, mIHC	Human, Mouse, Rat
	beta Catenin Antibody (YA584) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to beta Catenin.

HY-P87881

	β Catenin Antibody (YA7566)	WB, IHC-P, ICC/IF, IP, ELISA	Human, Mouse, Rat
	β Catenin Antibody (YA7566) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to β Catenin.

HY-P87830

	*Phospho-β Catenin* (Ser37) Antibody (YA7515)**	WB, ICC/IF, ELISA	Human, Mouse, Rat
	Phospho-β Catenin (Ser37) Antibody (YA7515) is a Rabbit-derived and non-conjugated IgG, Kappa monoclonal antibody, targeting to Phospho-β Catenin (Ser37).

HY-P86813

	CHD8 Antibody (YA6506) ATP dependent helicase CHD8 antibody; ATP-dependent helicase CHD8 antibody; Axis duplication inhibitor antibody; Beta catenin binding protein like antibody; CHD 8 antibody; CHD-8 antibody; chd8 antibody; CHD8_HUMAN antibody; Chromodomain helicase DNA binding protein 8 antibody; Chromodomain-helicase-DNA-binding protein 8 antibody; ATP dependent helicase CHD8 antibody; ATP-dependent helicase CHD8 antibody; Axis duplication inhibitor antibody; Beta catenin binding protein like antibody; CHD 8 antibody; CHD-8 antibody; chd8 antibody; CHD8_HUMAN antibody; Chromodomain helicase DNA binding protein 8 antibody; Chromodomain-helicase-DNA-binding protein 8 antibody; DKFZp686N17164 antibody; Duplin antibody; Helicase with SNF2 domain 1 antibody; HELSNF1 antibody; KIAA1564 antibody;	WB, ICC/IF, IHC-P, IP, ChIP	Human, Mouse, Rat
	CHD8 Antibody (YA6506) is a Rabbit-derived and non-conjugated IgG monoclonal antibody, targeting to CHD8.

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Host
Reactivity
Application
Dilution Ratio
Molecular Weight
Conjugation
Clonality
Immunogen
Appearance
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SwissProt ID
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Free Sample	Yes No
Size	* This product has been "discontinued". Optimized version of product available: / 在庫あり - + カートに追加お問い合わせ

製品番号	製品名		Classification

HY-185320A

Surbisiran sodium		siRNAs siRNA drugs
Surbisiran sodium is a siRNA with antineoplastic activity. It inhibits β-catenin synthesis.

HY-185320

Surbisiran		siRNAs siRNA drugs
Surbisiran is a siRNA with antineoplastic activity. It inhibits β-catenin synthesis.

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