β-Catenin modulator-9

Name: β-Catenin modulator-9
Brand: MedChemExpress
SKU: HY-185413
Rating: 4.5 (1 reviews)

Cat. No.: HY-185413 Purity: 99.22%: Data Sheet
COA

SDS
Handling Instructions
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β-Catenin modulator-9 (Compound IIa-2075) is a β-Catenin modulator. β-Catenin modulator-9 specifically targets the activity of the stable β-catenin pool and inhibits the Wnt signaling pathway. β-Catenin modulator-9 can be used in cancer-related research.

For research use only. We do not sell to patients.

β-Catenin modulator-9 Chemical Structure

CAS No. : 902167-39-9

Size	Stock	Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO ready for reconstitution	In-stock	Estimated Time of Arrival: December 31
Solution
10 mM * 1 mL in DMSO	In-stock	Estimated Time of Arrival: December 31
Solid
5 mg	In-stock	Estimated Time of Arrival: December 31
10 mg	In-stock	Estimated Time of Arrival: December 31
25 mg	In-stock	Estimated Time of Arrival: December 31
50 mg	In-stock	Estimated Time of Arrival: December 31
100 mg	In-stock	Estimated Time of Arrival: December 31
200 mg	Get quote
500 mg	Get quote

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Customer Review

Based on 1 publication(s) in Google Scholar

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•Related Screening Libraries:

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View All Wnt Isoform Specific Products:

View All Isoforms

Wnt1 Wnt3 Wnt5 Wnt7 Wnt11

Biological Activity
Purity & Documentation
References
Customer Review

Description

In Vitro

β-Catenin modulator-9 specifically targets the activity of the stable β-catenin pool and inhibits the Wnt signaling pathway^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

421.56

Formula

C₂₄H₂₇N₃O₂S

CAS No.

902167-39-9

Appearance

Solid

Color

White to off-white

SMILES

O=C(CSCC1=C(C)OC(C2=C(C)C=CC=C2)=N1)N3CCN(CC3)C4=CC=CC=C4

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	6 months
	-20°C	1 month

Solvent & Solubility

In Vitro:

DMSO : 50 mg/mL (118.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	2.3721 mL	11.8607 mL	23.7214 mL
5 mM	0.4744 mL	2.3721 mL	4.7443 mL
10 mM	0.2372 mL	1.1861 mL	2.3721 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

Purity & Documentation

Purity: 99.22%

Select Batch:

Data Sheet (269 KB) SDS (252 KB)

COA (248 KB) HNMR (273 KB) LCMS (353 KB)

Handling Instructions (2659 KB)

References

[1]. Ramanuj Dasgupta, et al. Oxazole and thiazole compounds as beta-catenin modulators and uses thereof. US20120264744A1. United States. 2012-04-17.

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

DMSO	1 mM	2.3721 mL	11.8607 mL	23.7214 mL	59.3035 mL
	5 mM	0.4744 mL	2.3721 mL	4.7443 mL	11.8607 mL
	10 mM	0.2372 mL	1.1861 mL	2.3721 mL	5.9304 mL
	15 mM	0.1581 mL	0.7907 mL	1.5814 mL	3.9536 mL
	20 mM	0.1186 mL	0.5930 mL	1.1861 mL	2.9652 mL
	25 mM	0.0949 mL	0.4744 mL	0.9489 mL	2.3721 mL
	30 mM	0.0791 mL	0.3954 mL	0.7907 mL	1.9768 mL
	40 mM	0.0593 mL	0.2965 mL	0.5930 mL	1.4826 mL
	50 mM	0.0474 mL	0.2372 mL	0.4744 mL	1.1861 mL
	60 mM	0.0395 mL	0.1977 mL	0.3954 mL	0.9884 mL
	80 mM	0.0297 mL	0.1483 mL	0.2965 mL	0.7413 mL
	100 mM	0.0237 mL	0.1186 mL	0.2372 mL	0.5930 mL