DC-TEAD3in03
DC-TEAD3in03 is a subtype-selective and covalent TEAD3 inhibitor with an IC50 of 0.16 μM. DC-TEAD3in03 exhibits the inhibitory activity on TEAD1/2/4 reduced by more than 100 times. DC-TEAD3in03 has the IC50 for TEAD3 of 1.15 μM in the GAL4-TEAD reporter gene experiment in cells, and it does not interfere with the β-catenin pathway. DC-TEAD3in03 reduces the growth rate of the zebrafish tail fin. DC-TEAD3in03 can be used to study the proportional growth of appendages in vertebrates.
For research use only. We do not sell to patients.
- Formula: C17H24N2O2
- Molecular Weight:288.38
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All YAP Isoforms
More
Biological Activity
|
TEAD3 0.16 μM (IC50) |
Chemical Information
-
Molecular Weight 288.38
-
Formula C17H24N2O2
-
SMILES
O=C(C=C)N1CN(CCCOCC2=CC=CC=C2)CCC1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)