1. Cell Cycle/DNA Damage
    Stem Cell/Wnt
    MAPK/ERK Pathway
  2. Casein Kinase
    ERK
  3. Longdaysin

Longdaysin 

Cat. No.: HY-18285 Purity: 99.92%
Handling Instructions

Longdaysin is a CK1α, CK1δ, and extracellular signal-regulated kinase 2 (ERK2) inhibitor with IC50s of  5.6 µM, 8.8 µM, and 52 µM, respectively.

For research use only. We do not sell to patients.

Longdaysin Chemical Structure

Longdaysin Chemical Structure

CAS No. : 1353867-91-0

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 121 In-stock
Estimated Time of Arrival: December 31
5 mg USD 110 In-stock
Estimated Time of Arrival: December 31
10 mg USD 180 In-stock
Estimated Time of Arrival: December 31
25 mg USD 390 In-stock
Estimated Time of Arrival: December 31
50 mg USD 690 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1200 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

* Please select Quantity before adding items.

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Description

Longdaysin is a CK1α, CK1δ, and extracellular signal-regulated kinase 2 (ERK2) inhibitor with IC50s of  5.6 µM, 8.8 µM, and 52 µM, respectively[1][2].

IC50 & Target[1]

CKIα

5.6 μM (IC50)

CKIδ

8.8 μM (IC50)

ERK2

52 μM (IC50)

Storage

4°C, protect from light

Solvent & Solubility
In Vitro: 

DMSO : 125 mg/mL (372.77 mM; Need ultrasonic)

H2O : < 0.1 mg/mL (insoluble)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9821 mL 14.9107 mL 29.8214 mL
5 mM 0.5964 mL 2.9821 mL 5.9643 mL
10 mM 0.2982 mL 1.4911 mL 2.9821 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (6.20 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% DMSO    90% corn oil

    Solubility: ≥ 2.08 mg/mL (6.20 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
Molecular Weight

335.33

Formula

C₁₆H₁₆F₃N₅

CAS No.

1353867-91-0

SMILES

FC(F)(F)C1=CC=CC(CNC2=NC=NC3=C2N=CN3C(C)C)=C1

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
Longdaysin
Cat. No.:
HY-18285
Quantity:

Longdaysin

Cat. No.: HY-18285