GSK3-IN-10
GSK3-IN-10 (Compound 4) is a multi-target inhibitor, that mainly targets GSK3α and GSK3β with IC50 of 1.0 nM and 2.0 nM. GSK3-IN-10 inhibits the activation of β-catenin, promotes the neuronal survival, and exhibits a protective effect against endoplasmic reticulum stress.
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- CAS No.: 844441-56-1
- Formule: C17H18F2N4O3
- Masse moléculaire:364.35
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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GSK-3α 1.0 nM (IC50) |
GSK-3β 2.0 nM (IC50) |
DYRK1B 47 nM (IC50) |
DYRK1A 170 nM (IC50) |
ICK 520 nM (IC50) |
CLK1 620 nM (IC50) |
CLK4 760 nM (IC50) |
DYRK2 800 nM (IC50) |
CLK2 800 nM (IC50) |
CDKL5 840 nM (IC50) |
JNK3 2900 nM (IC50) |
CDK4 3800 nM (IC50) |
Chemical Information
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CAS No. 844441-56-1
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Masse moléculaire 364.35
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Formule C17H18F2N4O3
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SMILES
O=C(C1=NNC=C1NC(C2=C(F)C=CC=C2F)=O)NCC3CCOCC3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GSK3-IN-10 Related Classifications
HY-172198 Related Classifications
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