844441-56-1
844441-56-1
Chemical Structure
GSK3-IN-10
- CAS No.: 844441-56-1
- Formula:C17H18F2N4O3
- Molecular Weight:364.35
InChIKey: OCQCKUTZHBQNEI-UHFFFAOYSA-N
SMILES: O=C(C1=NNC=C1NC(C2=C(F)C=CC=C2F)=O)NCC3CCOCC3
Biological Activity: GSK3-IN-10 (Compound 4) is a multi-target inhibitor, that mainly targets GSK3α and GSK3β with IC50 of 1.0 nM and 2.0 nM. GSK3-IN-10 inhibits the activation of β-catenin, promotes the neuronal survival, and exhibits a protective effect against endoplasmic reticulum stress[1].
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GSK3-IN-10 | GSK3-IN-10 (Compound 4) is a multi-target inhibitor, that mainly targets GSK3α and GSK3β with IC50 of 1.0 nM and 2.0 nM. GSK3-IN-10 inhibits the activation of β-catenin, promotes the neuronal survival, and exhibits a protective effect against endoplasmic reticulum stress. | |||||||||||||||||||||
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References
Keywords
