1. Signaling Pathways
  2. Protein Tyrosine Kinase/RTK
  3. DYRK
  4. DYRK2 Isoform

DYRK2

 

DYRK2 Related Products (5):

Cat. No. Product Name Effect Purity
  • HY-U00439A
    Protein kinase inhibitor 1 hydrochloride
    Inhibitor ≥98.0%
    Protein kinase inhibitor 1 hydrochloride is a potent HIPK2 inhibitor, with IC50s of 136 and 74 nM for HIPK1 and HIPK2, and a Kd of 9.5 nM for HIPK2.
  • HY-112296
    T025
    Inhibitor 98.61%
    T025 is an orally active and highly potent inhibitor of Cdc2-like kinase (CLKs), with Kd values of 4.8, 0.096, 6.5, 0.61, 0.074, 1.5 and 32 nM for CLK1, CLK2, CLK3, CLK4, DYRK1A, DYRK1B and DYRK2, respectively.
  • HY-111379
    EHT 5372
    Inhibitor
    EHT 5372 is a highly potent and selective inhibitor of DYRK’s family kinases with IC50s of 0.22, 0.28, 10.8, 93.2, 22.8, 88.8, 59.0, 7.44, 221 nM for DYRK1A, DYRK1B , DYRK2, DYRK3, CLK1, CLK2, CLK4, GSK-3α, GSK-3β.
  • HY-147066
    Dyrk1A-IN-4
    Inhibitor
    Dyrk1A-IN-4 (compound 48) is a potent and orally active DYRK1A and DYRK2 inhibitor with IC50s of 2 nM and 6 nM, respectively.
  • HY-146221
    Dyrk1A-IN-5
    Inhibitor
    Dyrk1A-IN-5 (compound 5j) is a potent and selective DYRK1A inhibitor, with an IC50 of 6 nM.