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DYRK2-IN-2

DYRK2-IN-2 (Compound C17) is a selective inhibitor of DYRK2, with its IC50 value being 40.3 nM. The inhibitory activity of DYRK2-IN-2 on DYRK1A (IC50 = 1842 nM), DYRK1B (IC50 = 1335 nM), DYRK4 (IC50 = 1931 nM), DYRK3 (IC50 = 112 nM), and CLKs (IC50 = 540-6496 NM) is relatively low. DYRK2-IN-2 inhibits the phosphorylation of Tau protein at Thr212 and shows moderate cytotoxicity in HT22 cells. DYRK2-IN-2 can be used in cancer research.

For research use only. We do not sell to patients.

  • CAS No.: 2416195-65-6
  • Formula: C21H24N2O3S
  • Molecular Weight:384.49
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • DYRK2-IN-2 Chemical Structure
    DYRK2-IN-2 Chemical Structure
CAS No.: 2416195-65-6
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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  • DYRK2-IN-2 Chemical Structure
    DYRK2-IN-2 Chemical Structure
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  • DYRK2-IN-2