DYRK3
DYRK3, originally described as the erythroid-specific kinase REDK, shows a striking expression pattern concentrated in erythroid cells and in testis. Beyond erythroid differentiation, DYRK3 has a distinctive cytoplasmic role: during stress it accumulates in stress granules, and on stress relief it is released to activate mTORC1, thereby helping cells restore translation and proliferative signaling. Like other family members, it activates through autophosphorylation of an activation-loop tyrosine and then phosphorylates serine/threonine sites. DYRK3 is therefore a specialized stress-sensing kinase rather than a broad developmental regulator such as DYRK1A. Recombinant DYRK3 serves translational-control research and inhibitor selectivity panels.
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DYRK3 Recombinant Proteins (1)
- Species:
- Source:
Recombinant Protein Expression Service
- Codon Optimization
- Gene Synthesis
- Construction of Expression Vector
- Strain Screening
- Protein Expression
- Purification & QC
- Protein Delivery
- Formula: Human
- Molecular Weight: Sf9 insect cells
The EpCAM/TROP1 protein serves as an important homogeneous interacting molecule that promotes direct contact between intestinal epithelial cells (IEC) and intraepithelial lymphocytes (IEL) in the mucosal epithelium. This feature helps establish an immune barrier against mucosal infections. EpCAM/TROP1 Protein, Human (His-SUMO) is the recombinant human-derived EpCAM/TROP1 protein, expressed by E. coli , with N-6*His, N-SUMO labeled tag.
