1. Cell Cycle/DNA Damage
  2. CDK

T025 

Cat. No.: HY-112296
Handling Instructions

T025 is an orally available and highly potent Cdc2-like kinase (CLK) inhibitor with Kds of 4.8, 0.096, 6.5, and 0.61 nM for CLK1, CLK2, CLK3, and CLK4, respectively.

For research use only. We do not sell to patients.

T025 Chemical Structure

T025 Chemical Structure

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Customer Review

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

T025 is an orally available and highly potent Cdc2-like kinase (CLK) inhibitor with Kds of 4.8, 0.096, 6.5, and 0.61 nM for CLK1, CLK2, CLK3, and CLK4, respectively.

IC50 & Target

Kd: 4.8 nM (CLK1), 0.096 nM (CLK2), 6.5 nM (CLK3), 0.61 nM (CLK4)[1]

References
Molecular Weight

382.42

Formula

C₂₁H₁₈N₈

SMILES

CNC1=NC(NCC2=NC=CC=N2)=C(C(C3=CC=C(N=CC=C4)C4=C3)=CN5)C5=N1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

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Product Name:
T025
Cat. No.:
HY-112296
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T025

Cat. No.: HY-112296