1025821-33-3
1025821-33-3
Chemical Structure
GSK-626616
- CAS No.: 1025821-33-3
- Formula:C18H10Cl2N4OS
- Molecular Weight:401.27
IUPAC Name: (Z)-2-((2,6-dichlorophenyl)amino)-5-(quinoxalin-6-ylmethylene)thiazol-4(5H)-one
InChIKey: RJPNRXFBYZVRIB-DHDCSXOGSA-N
SMILES: O=C1N=C(NC2=C(Cl)C=CC=C2Cl)S/C1=C\C3=CC=C4N=CC=NC4=C3
Biological Activity: GSK-626616 is a potent, orally bioavailable inhibitor of DYRK3 (IC50=0.7 nM). GSK-626616 inhibits other members of the DYRK family (e.g., DYRK1A and DYRK2) with similar potency, which is a potential therapy for the treatment of anemia[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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GSK-626616 | 99.97% | GSK-626616 is a potent, orally bioavailable inhibitor of DYRK3 (IC50=0.7 nM). GSK-626616 inhibits other members of the DYRK family (e.g., DYRK1A and DYRK2) with similar potency, which is a potential therapy for the treatment of anemia. | ||||||||||||||||||||
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GSK-626616 (Standard) | ≥98% | GSK-626616 (Standard) is the analytical standard of GSK-626616 (HY-105309). This product is intended for research and analytical applications. GSK-626616 is a potent, orally bioavailable inhibitor of DYRK3 (IC50=0.7 nM). GSK-626616 inhibits other members of the DYRK family (e.g., DYRK1A and DYRK2) with similar potency, which is a potential therapy for the treatment of anemia. | ||||||||||||||||||||
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Structural Analogs
-
Similarity Score 0.57
HY-145081Pitnot-2 -
Similarity Score 0.56
HY-115977Aldose reductase-IN-3 -
Similarity Score 0.56
HY-12529Ro-3306 -
Similarity Score 0.55
HY-10109AS-605240 -
Similarity Score 0.54
HY-15705GPR35 agonist 2 -
Similarity Score 0.52
HY-48869PI3K-IN-46 -
Similarity Score 0.51
HY-146138EGFR-IN-57 -
Similarity Score 0.50
HY-12036GSK1059615 -
Similarity Score 0.49
HY-115604Pitstop 2 -
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