1784281-97-5
Chemical Structure
LDN-209929 dihydrochloride
- CAS No.: 1784281-97-5
- Formula:C17H19Cl3N2OS
- Molecular Weight:405.77
IUPAC Name: 3-((2-chloro-7-methoxyacridin-9-yl)thio)propan-1-amine dihydrochloride
InChIKey: WOCCOXNODBCCGK-UHFFFAOYSA-N
SMILES: NCCCSC1=C(C=C(Cl)C=C2)C2=NC3=CC=C(OC)C=C31.[H]Cl.[H]Cl
Biological Activity: LDN-209929 dihydrochloride is a potent and selective haspin kinase inhibitor (IC50=55 nM) with180-fold selectivity verses DYRK2 (IC50=9.9 μM). LDN-209929 is a optimized analogue of LDN-192960 (HY-13455)[2].
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LDN-209929 dihydrochloride | 98.33% | LDN-209929 dihydrochloride is a potent and selective haspin kinase inhibitor (IC50=55 nM) with180-fold selectivity verses DYRK2 (IC50=9.9 μM). LDN-209929 is a optimized analogue of LDN-192960 (HY-13455). | ||||||||||||||||||||
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Keywords