YK-2-69
Based on 1 Customer Validation
YK-2-69 is a highly selective DYRK2 inhibitor with an IC50 value of 9 nM. YK-2-69 specifically interacts with Lys-231 and Lys-234 of DYRK2 and can be utilized in researches related to prostate cancer.
For research use only. We do not sell to patients.
- Purity: 99.44%
- CAS No.: 2619846-89-6
- Formula: C25H27FN8OS
- Molecular Weight:506.60
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Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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DYRK2 9 nM (IC50) |
Chemical Information
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CAS No. 2619846-89-6
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Appearance Solid
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Molecular Weight 506.60
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Formula C25H27FN8OS
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Color White to light yellow
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SMILES
O=C(N1CCN(CC1)CC)C2=CN=C(NC3=NC(C4=CC5=C(N=C(N(C)C)S5)C=C4)=C(F)C=N3)C=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 5.83 mg/mL (11.51 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.9739 mL | 9.8697 mL | 19.7394 mL | 49.3486 mL |
| 5 mM | 0.3948 mL | 1.9739 mL | 3.9479 mL | 9.8697 mL | |
| 10 mM | 0.1974 mL | 0.9870 mL | 1.9739 mL | 4.9349 mL |