1685235-41-9
1685235-41-9
Chemical Structure
Dyrk1A-IN-5
- CAS No.: 1685235-41-9
- Formula:C16H9IN2O2
- Molecular Weight:388.16
IUPAC Name: (3R)-D-valinic acid
InChIKey: SDRAETFVRBBLOB-UHFFFAOYSA-N
SMILES: O=C(C1=NC2=CC=CC=C2C3=C1C4=C(N3)C(I)=CC=C4)O
Biological Activity: Dyrk1A-IN-5 (Compound 5j) is a potent and selective DYRK1A inhibitor, with an IC50 of 6 nM. yrk1A-IN-5 exhibits significant selectivity for DYRK1B (IC50 = 600 nM) and CLK1 (IC50 = 500 nM), but shows almost no inhibition of DYRK2 (IC50 > 10 μM). Dyrk1A-IN-5 can be used for Down syndrome research[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Dyrk1A-IN-5 | 98.06% | Dyrk1A-IN-5 (Compound 5j) is a potent and selective DYRK1A inhibitor, with an IC50 of 6 nM. yrk1A-IN-5 exhibits significant selectivity for DYRK1B (IC50 = 600 nM) and CLK1 (IC50 = 500 nM), but shows almost no inhibition of DYRK2 (IC50 > 10 μM). Dyrk1A-IN-5 can be used for Down syndrome research. | ||||||||||||||||||||
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References
Keywords
