DHPCC-9
DHPCC-9 acts as an inhibitor of Pim kinase.
For research use only. We do not sell to patients.
- CAS No.: 1192248-37-5
- Formula: C15H10N2O
- Molecular Weight:234.25
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| DU-145 | IC50 |
26 μM
Compound: 9
|
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin dye reduction assay
|
[PMID: 19788246] |
| DU-145 | IC50 |
26 μM
Compound: A
|
Cytotoxicity against human DU145 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human DU145 cells after 48 hrs by resazurin reduction test
|
[PMID: 20728368] |
| DU-145 | IC50 |
26 μM
Compound: A
|
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin reduction test
Antiproliferative activity against human DU145 cells after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
| Fibroblast | IC50 |
21 μM
Compound: 9
|
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin dye reduction assay
|
[PMID: 19788246] |
| Fibroblast | IC50 |
21 μM
Compound: A
|
Cytotoxicity against human fibroblasts after 48 hrs by resazurin reduction test
Cytotoxicity against human fibroblasts after 48 hrs by resazurin reduction test
|
[PMID: 20728368] |
| Fibroblast | IC50 |
21 μM
Compound: A
|
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test
Antiproliferative activity against human fibroblasts after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
| PA-1 | IC50 |
4.5 μM
Compound: 9
|
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin dye reduction assay
|
[PMID: 19788246] |
| PA-1 | IC50 |
4.5 μM
Compound: A
|
Cytotoxicity against human PA1 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human PA1 cells after 48 hrs by resazurin reduction test
|
[PMID: 20728368] |
| PA-1 | IC50 |
4.5 μM
Compound: A
|
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test
Antiproliferative activity against human PA1 cells after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
| PC-3 | IC50 |
9.5 μM
Compound: 9
|
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin dye reduction assay
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin dye reduction assay
|
[PMID: 19788246] |
| PC-3 | IC50 |
9.5 μM
Compound: A
|
Cytotoxicity against human PC3 cells after 48 hrs by resazurin reduction test
Cytotoxicity against human PC3 cells after 48 hrs by resazurin reduction test
|
[PMID: 20728368] |
| PC-3 | IC50 |
9.5 μM
Compound: A
|
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin reduction test
Antiproliferative activity against human PC3 cells after 48 hrs by resazurin reduction test
|
[PMID: 22982527] |
Chemical Information
-
CAS No. 1192248-37-5
-
Molecular Weight 234.25
-
Formula C15H10N2O
-
SMILES
O=CC1=CNC2=C1C=CC3=C2NC4=C3C=CC=C4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)