TWS119 TFA

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TWS119 TFA is a specific inhibitor of GSK-3β, with an IC₅₀ of 30 nM, and activates the wnt/β-catenin pathway.

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TWS119 TFA Chemical Structure

CAS No. : 1507095-58-0

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Other In-stock Forms of TWS119 TFA:

TWS119

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TWS119 In-stock

21 Publications Citing Use of MCE TWS119 TFA

: TWS119 TFA purchased from MedChemExpress. Usage Cited in: FASEB J. 2023 Mar;37(3):e22821. [Abstract]; TWS119 substantially increases NF-κB phosphorylation in NK-92 cells.

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Description	TWS119 TFA is a specific inhibitor of GSK-3β, with an IC₅₀ of 30 nM, and activates the wnt/β-catenin pathway.
Molecular Weight	546.38
Formula	C₂₂H₁₆F₆N₄O₆
CAS No.	1507095-58-0
SMILES	OC1=CC=CC(OC2=C3C(NC(C4=CC=CC(N)=C4)=C3)=NC=N2)=C1.OC(C(F)(F)F)=O.OC(C(F)(F)F)=O
Shipping	Room temperature in continental US; may vary elsewhere.
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation	Data Sheet (273 KB) Handling Instructions (2659 KB)
References	[1]. Hochstrasser RM. Two-dimensional spectroscopy at infrared and optical frequencies. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14190-6. [Content Brief] [2]. Hochstrasser RM. Two-dimensional spectroscopy at infrared and optical frequencies. Proc Natl Acad Sci U S A. 2007 Sep 4;104(36):14190-6. [Content Brief]

TWS119 TFA Related Classifications

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This equation is commonly abbreviated as: C₁V₁ = C₂V₂

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Do most proteins show cross-species activity?
Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

TWS1191507095-58-0TWS 119TWS-119Othersembryonic stem cellsglycogen synthase kinase-3βsmall moleculesInhibitorinhibitorinhibit

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TWS119 TFA

Other Forms of TWS119 TFA:

TWS119 TFA Related Antibodies

21 Publications Citing Use of MCE TWS119 TFA

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Biological Activity

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