1. Stem Cell/Wnt
  2. Wnt
  3. HLY78

HLY78 

Cat. No.: HY-122816 Purity: 98.38%
Handling Instructions

HLY78 is an activator of the Wnt/β-catenin signaling pathway, which targets the DIX domain of Axin and potentiates the Axin-LRP6 association to promote Wnt signaling transduction.

For research use only. We do not sell to patients.

HLY78 Chemical Structure

HLY78 Chemical Structure

CAS No. : 854847-61-3

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Free Sample (0.5-1 mg)   Apply now  
5 mg USD 160 In-stock
Estimated Time of Arrival: December 31
10 mg USD 270 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

HLY78 is an activator of the Wnt/β-catenin signaling pathway, which targets the DIX domain of Axin and potentiates the Axin-LRP6 association to promote Wnt signaling transduction[1].

IC50 & Target

Wnt/β-catenin[1]

Molecular Weight

267.32

Formula

C₁₇H₁₇NO₂

CAS No.

854847-61-3

SMILES

CCC1=CC=CC2=C1N(CC3=CC4=C(C=C32)OCO4)C

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 26 mg/mL (97.26 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.7408 mL 18.7042 mL 37.4083 mL
5 mM 0.7482 mL 3.7408 mL 7.4817 mL
10 mM 0.3741 mL 1.8704 mL 3.7408 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.08 mg/mL (7.78 mM); Clear solution

*All of the co-solvents are provided by MCE.
References

Purity: 98.38%

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Keywords:

HLY78HLY 78HLY-78WntInhibitorinhibitorinhibit

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HLY78
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HY-122816
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