1. Stem Cell/Wnt
  2. Wnt
    β-catenin
  3. NLS-StAx-h

NLS-StAx-h 

Cat. No.: HY-P2272
Handling Instructions

NLS-StAx-h is a selective, stapled peptide inhibitor of Wnt signaling with an IC50 of 1.4 μM. NLS-StAx-h efficiently inhibits β-catenin-transcription factor interactions. NLS-StAx-h inhibits proliferation and migration of colorectal cancer cells.

For research use only. We do not sell to patients.

Custom Peptide Synthesis

NLS-StAx-h Chemical Structure

NLS-StAx-h Chemical Structure

Size Stock
100 μg Get quote

* Please select Quantity before adding items.

Top Publications Citing Use of Products
  • Biological Activity

  • Purity & Documentation

  • References

  • Customer Review

Description

NLS-StAx-h is a selective, stapled peptide inhibitor of Wnt signaling with an IC50 of 1.4 μM. NLS-StAx-h efficiently inhibits β-catenin-transcription factor interactions. NLS-StAx-h inhibits proliferation and migration of colorectal cancer cells[1].

IC50 & Target[1]

Wnt

1.4 μM (IC50)

In Vitro

NLS-StAx-h (10 μM, 72 hr) reduces the viability of both SW-480 and DLD-1 by more than 80%. NLS-StAx-h results in gene expression changes[1].

Molecular Weight

3445.26

Formula

C₁₆₁H₂₇₅N₅₅O₂₉

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

References
  • No file chosen (Maximum size is: 1024 Kb)
  • If you have published this work, please enter the PubMed ID.
  • Your name will appear on the site.
  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

NLS-StAx-hWntβ-cateninBeta cateninstapledpeptideproliferationmigrationcolorectalcancerInhibitorinhibitorinhibit

Your Recently Viewed Products:

Inquiry Online

Your information is safe with us. * Required Fields.

Product Name

 

Salutation

Applicant Name *

 

Email address *

Phone number *

 

Organization name *

Country or Region *

 

Requested quantity *

Remarks

Bulk Inquiry

Inquiry Information

Product Name:
NLS-StAx-h
Cat. No.:
HY-P2272
Quantity:
MCE Japan Authorized Agent: