2. Metabolic Enzyme/Protease
  3. MMP
  4. NNGH

NNGH is a stromelysin-1 (MMP-3) inhibitor. MMP-3 is both a direct transcriptional target and a necessary contributor of the Wnt/β-catenin signaling pathway. Matrix metalloproteinases (MMPs) play a well-defined role in later stages of tumor progression.

For research use only. We do not sell to patients.

NNGH Chemical Structure

NNGH Chemical Structure

CAS No. : 161314-17-6

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NNGH Related Antibodies

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MMP-1 MMP-2 MMP-3 MMP-8 MMP-9 MMP-13 MMP-14 MMP-17 ADAM10 ADAM17 MMP-7 MMP-12 MMP-10 MMP ADAM8

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Description

NNGH is a stromelysin-1 (MMP-3) inhibitor. MMP-3 is both a direct transcriptional target and a necessary contributor of the Wnt/β-catenin signaling pathway. Matrix metalloproteinases (MMPs) play a well-defined role in later stages of tumor progression[1].

Molecular Weight

316.37

Formula

C13H20N2O5S
CAS No.
SMILES

ONC(CN(CC(C)C)S(C1=CC=C(C=C1)OC)(=O)=O)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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NNGH Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

NNGH161314-17-6MMPMatrix metalloproteinasesstromelysin-1MMP-3 inhibitorWnt/β-catenin signaling pathwaytumor progressionInhibitorinhibitorinhibit

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