Fluc-IN-1
Based on 1 Customer Validation
Fluc-IN-1 (Compound 3) is an inhibitor for firefly luciferase with an IC50 of 25 nM. Fluc-IN-1 inhibits WNT/β-catenin signaling pathway with an IC50 of 33 nM (measuring by TOPFlash assay).
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 98.44%
- CAS No.: 2940242-10-2
- 화학식: C26H23N3O2S2
- 분자량:473.61
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
제품 설명
IC50 & Target
IC50: 25 nM (firefly luciferase)
Chemical Information
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CAS No. 2940242-10-2
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Appearance Solid
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분자량 473.61
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화학식 C26H23N3O2S2
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Color White to off-white
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SMILES
O=C(C1=CC=C(C)C=C1C)NC2=CC=C(C=C2)SCC(NC3=NC(C4=CC=CC=C4)=CS3)=O
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 116.67 mg/mL (246.34 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.1114 mL | 10.5572 mL | 21.1144 mL | 52.7860 mL |
| 5 mM | 0.4223 mL | 2.1114 mL | 4.2229 mL | 10.5572 mL | |
| 10 mM | 0.2111 mL | 1.0557 mL | 2.1114 mL | 5.2786 mL | |
| 15 mM | 0.1408 mL | 0.7038 mL | 1.4076 mL | 3.5191 mL | |
| 20 mM | 0.1056 mL | 0.5279 mL | 1.0557 mL | 2.6393 mL | |
| 25 mM | 0.0845 mL | 0.4223 mL | 0.8446 mL | 2.1114 mL | |
| 30 mM | 0.0704 mL | 0.3519 mL | 0.7038 mL | 1.7595 mL | |
| 40 mM | 0.0528 mL | 0.2639 mL | 0.5279 mL | 1.3197 mL | |
| 50 mM | 0.0422 mL | 0.2111 mL | 0.4223 mL | 1.0557 mL | |
| 60 mM | 0.0352 mL | 0.1760 mL | 0.3519 mL | 0.8798 mL | |
| 80 mM | 0.0264 mL | 0.1320 mL | 0.2639 mL | 0.6598 mL | |
| 100 mM | 0.0211 mL | 0.1056 mL | 0.2111 mL | 0.5279 mL |