1. Stem Cell/Wnt
  2. Wnt
    β-catenin
  3. DK419

DK419 

Cat. No.: HY-112799
Handling Instructions

DK419 is a potent and orally active Wnt/β-catenin signaling inhibitor, with an IC50 of 0.19 μM. DK419 reduces protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin and induces production of pAMPK.

For research use only. We do not sell to patients.

DK419 Chemical Structure

DK419 Chemical Structure

CAS No. : 2102672-22-8

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Description

DK419 is a potent and orally active Wnt/β-catenin signaling inhibitor, with an IC50 of 0.19 μM. DK419 reduces protein lelvels of Axin2, β-catenin, c-Myc, Cyclin D1 and Survivin and induces production of pAMPK[1].

IC50 & Target

Wnt/β-catenin[1]

Molecular Weight

407.70

Formula

C₁₆H₈ClF₆N₃O

CAS No.

2102672-22-8

SMILES

O=C(C1=C2C(N=C(C(F)(F)F)N2)=CC(Cl)=C1)NC3=CC=C(C(F)(F)F)C=C3

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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DK419
Cat. No.:
HY-112799
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