1. Immunology/Inflammation
  2. NOD-like Receptor (NLR)
    Aryl Hydrocarbon Receptor
  3. Cardamonin

Cardamonin (Synonyms: Cardamomin; Alpinetin chalcone)

Cat. No.: HY-N0279 Purity: 98.54%
Handling Instructions

Cardamonin (Cardamomin), a natural flavone isolated from Alpinia katsumadai Hayata, acts as an aryl hydrocarbon receptor (AhR) activator. Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway.

For research use only. We do not sell to patients.

Cardamonin Chemical Structure

Cardamonin Chemical Structure

CAS No. : 18956-16-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 75 In-stock
Estimated Time of Arrival: December 31
5 mg USD 68 In-stock
Estimated Time of Arrival: December 31
10 mg USD 116 In-stock
Estimated Time of Arrival: December 31
50 mg USD 350 In-stock
Estimated Time of Arrival: December 31
100 mg   Get quote  
200 mg   Get quote  

* Please select Quantity before adding items.

Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Cardamonin (Cardamomin), a natural flavone isolated from Alpinia katsumadai Hayata, acts as an aryl hydrocarbon receptor (AhR) activator. Cardamonin alleviates inflammatory bowel disease by the inhibition of NLRP3 inflammasome activation via an AhR/Nrf2/NQO1 pathway[1].

IC50 & Target

NLRP3

 

Molecular Weight

270.28

Formula

C₁₆H₁₄O₄

CAS No.

18956-16-6

SMILES

O=C(C1=C(OC)C=C(O)C=C1O)/C=C/C2=CC=CC=C2

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

DMSO : 130 mg/mL (480.98 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.6999 mL 18.4993 mL 36.9987 mL
5 mM 0.7400 mL 3.6999 mL 7.3997 mL
10 mM 0.3700 mL 1.8499 mL 3.6999 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% DMSO    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.17 mg/mL (8.03 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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Keywords:

CardamoninCardamomin Alpinetin chalconeNOD-like Receptor (NLR)Aryl Hydrocarbon ReceptorAhRInhibitorinhibitorinhibit

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Product name:
Cardamonin
Cat. No.:
HY-N0279
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