SKL2001 (Standard)
SKL2001 (Standard) is the analytical standard of SKL2001 (HY-101085). This product is intended for research and analytical applications. SKL2001 is an agonist of the Wnt/β-catenin pathway, with anti-cancer activity. SKL2001 stabilizes intracellular β-catenin via disruption of the Axin/β-catenin interaction.
For research use only. We do not sell to patients.
- CAS No.: 909089-13-0
- Formula: C14H14N4O3
- Molecular Weight:286.29
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 909089-13-0
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Molecular Weight 286.29
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Formula C14H14N4O3
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SMILES
O=C(C1=NOC(C2=CC=CO2)=C1)NCCCN3C=CN=C3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Gwak J, et al. Small molecule-based disruption of the Axin/β-catenin protein complex regulates mesenchymal stem cell differentiation. ell Res. 2012 Jan;22(1):237-47. [Content Brief]
[2]. Ohashi W, et al. SKL2001 suppresses colon cancer spheroid growth through regulation of the E-cadherin/β-Catenin complex. Biochem Biophys Res Commun. 2017 Nov 25;493(3):1342-1348. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)