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rac-

" in MedChemExpress (MCE) Product Catalog:

834

Inhibitors & Agonists

2

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52

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10

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64

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18

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215

Isotope-Labeled Compounds

29

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7

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26

Oligonucleotides

Targets Recommended:
Cat. No. Product Name Target Research Areas Chemical Structure
  • HY-15448A

    (rac)-VX-661

    CFTR Inflammation/Immunology
    (Rac)-Tezacaftor ((Rac)-VX-661) is a racemate of Tezacaftor (HY-15448). Tezacaftor is a F508del CFTR corrector. (Rac)-Tezacaftor can be used for the research of cystic fibrosis .
    (Rac)-Tezacaftor
  • HY-175341

    Acyltransferase Ras Akt Cancer
    Rac1-IN-5 is a specific, reversible inhibitor of RAC1 (KD = 30 nM). Rac1-IN-5 competes with guanine nucleotides for specific binding to RAC proteins, effectively blocking RAC1 activity and RAC1-dependent cellular functions. Rac1-IN-5 exhibits anti-tumor metastasis effects in vivo and can improve survival. Rac1-IN-5 can be used to study invasive cancers such as triple-negative breast cancer and colon cancer .
    Rac1-IN-5
  • HY-N0585
    (Rac)-Norcantharidin
    1 Publications Verification

    (rac)-NCTD

    Apoptosis Cancer
    (Rac)-Norcantharidin ((Rac)-NCTD) is the racemic form of Norcantharidin. Norcantharidin is a demethylated derivative of Cantharidin (HY-N0209) and has antitumor activity .
    (Rac)-Norcantharidin
  • HY-107501

    (rac)-1-Oleoyl-sn-glycero-3-phosphate sodium; (rac)-1-Oleoyl-LPA sodium

    Drug Isomer Neurological Disease
    (Rac)-1-Oleoyl lysophosphatidic acid ((Rac)-1-Oleoyl-sn-glycero-3-phosphate) sodium is the racemic isomer of 1-Oleoyl lysophosphatidic acid sodium (HY-107614) .
    (Rac)-1-Oleoyl lysophosphatidic acid sodium
  • HY-119486A

    (rac)-PF-06649751; (rac)-CVL-751

    Dopamine Receptor Arrestin Neurological Disease
    (Rac)-Tavapadon ((Rac)-PF-06649751) is a potent and selective noncatechol dopamine D1 receptor agonist. (Rac)-Tavapadon displays potent full agonism in the GS activation assay as well as partial agonism in the β-arrestin2 recruitment assay (GS-cAMP, EC50=0.8 nM; β-arrestin2, EC50=68 nM). (Rac)-Tavapadon has antiparkinsonian activity .
    (Rac)-Tavapadon
  • HY-125287

    (rac)-UCB0599; NPT200-11

    α-synuclein Neurological Disease
    (Rac)-Minzasolmin ((Rac)-UCB0599; NPT200-11) is a blood-brain barrier penetrated alpha-synuclein (ASYN) misfolding inhibitor. (Rac)-Minzasolmin acts on the early stage of ASYN aggregation process, by replacing the membrane-bound oligomers ASYN, allowing them to revert to the monomeric form, while preventing pathological aggregation. (Rac)-Minzasolmin effectively improves the ASYN deposition in the retina and the neuro-pathological indicators in two α-synuclein transgenic mouse models. (Rac)-Minzasolmin can be used for the studies of Parkinson's disease (PD) and dementia with Lewy bodies (DLB) .
    (Rac)-Minzasolmin
  • HY-W062703S

    (rac)-INCB18424-d9; Ruxotinib racemate-d9

    Isotope-Labeled Compounds JAK Cancer
    (Rac)-Ruxolitinib D9 ((Rac)-INCB18424 D9) is the deuterium labeled (Rac)-Ruxolitinib. (Rac)-Ruxolitinib is a JAK2 inhibitor .
    (Rac)-Ruxolitinib-d9
  • HY-136913

    (rac)-Betuligenol

    Endogenous Metabolite Inflammation/Immunology
    (Rac)-Rhododendrol ((Rac)-Betuligenol) is an aromatic compound with pro-oxidant activity. (Rac)-Rhododendrol may be useful in the suppression of liver diseases. (Rac)-Rhododendrol can be toxic to melanocytes, leading to cell death. The metabolite of (Rac)-Rhododendrol, RD-quinone, is cytotoxic and causes enzyme inactivation and endoplasmic reticulum stress by binding to thiol proteins. (Rac)-Rhododendrol-derived melanin exhibits potent pro-oxidant activity and may cause oxidative stress .
    (Rac)-Rhododendrol
  • HY-76570

    (rac)-Desfesoterodine; (rac)-PNU-200577

    mAChR Neurological Disease
    (Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine), an active metabolite of Tolterodine, is a mAChR antagonist (Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively). (Rac)-5-Hydroxymethyl Tolterodine can be used for overactive bladder research .
    (Rac)-5-Hydroxymethyl Tolterodine
  • HY-117884

    Apoptosis Cancer
    (Rac)-CCT 250863 (compound rac-21) is a selective and reversible NEK 2 inhibitor with an IC50 of 0.073 µM. (Rac)-CCT 250863 shows good effects of inducing cell cycle arrest and also can antiproliferative in cells (Pomalidomide sensitive/resistant). (Rac)-CCT 250863 induces apoptosis when combines with Pomalidomide .
    (Rac)-CCT 250863
  • HY-75124
    (Rac)-AZD 6482
    1 Publications Verification

    (rac)-KIN-193

    PI3K Autophagy Cancer
    (Rac)-AZD 6482 ((Rac)-KIN-193) is the racemate of AZD 6482. AZD 6482 is a potent and selective p110β inhibitor with an IC50 of 0.69 nM.
    (Rac)-AZD 6482
  • HY-158304

    Ras Cancer
    Rac1-IN-4 (Cas: 2924486-45-1) is a Rac1 inhibitor .
    Rac1-IN-4
  • HY-156668

    Ras Cardiovascular Disease
    Rac1-IN-3 (Compound 2) is a Rac1 inhibitor with an IC50 of 46.1 μM .
    Rac1-IN-3
  • HY-U00360

    (rac)-Netazepide; (rac)-YF 476; (rac)-YM-220

    Cholecystokinin Receptor Metabolic Disease
    (Rac)-Sograzepide is an antagonist of cholecystokinin B (CCK-B) receptor, and has the potential of reducing the secretion of gastric acid.
    (Rac)-Sograzepide
  • HY-141749S

    (rac)-CLPM-d4; (rac)-SR 26334-d4

    Isotope-Labeled Compounds Others
    (Rac)-Clopidogrel carboxylic acid-d4 is the deuterium labeled (Rac)-Clopidogrel carboxylic acid .
    (Rac)-Clopidogrel carboxylic acid-d4
  • HY-16023B

    EM-343; (rac)-EM-652

    Estrogen Receptor/ERR Cancer
    (Rac)-Acolbifene (EM-343; (Rac)-EM-652) is the racemic form of EM652 (estrogen receptor?antagonist), has anti-estrogenic and estrogenic activities. (Rac)-Acolbifene (EM-343; (Rac)-EM-652) contains a piperidine ring, shows good pharmacological profile,relative binding affinity (RBA)=380 .
    (Rac)-Acolbifene
  • HY-118426

    (rac)-IND 58359; (rac)-R115777

    Farnesyl Transferase Ras Cancer
    (Rac)-Tipifarnib ((Rac)-IND 58359; (Rac)-R115777) is a potent farnesyl protein transferase inhibitor that specifically targets the pro-tailation process of Ras proteins. (Rac)-Tipifarnib showed significant in vivo antitumor effects after oral administration to mice .
    (Rac)-Tipifarnib
  • HY-W391625

    (rac)-Epiligulyl oxide

    Fungal Cancer
    (Rac)-Dehydrocostus Lactone ((Rac)-Epiligulyl oxide) is a natural product with antiparasitic activity. (Rac)-Dehydrocostus Lactone can significantly inhibit the growth of Trypanosoma brucei rhodesiense. (Rac)-Dehydrocostus Lactone exhibits a broad spectrum of biological effects, including anti-inflammatory, anticancer, antiviral and antimicrobial activities. (Rac)-Dehydrocostus Lactone also has antifungal, antioxidant, antidiabetic, antiulcer and antihelminthic effects. (Rac)-Dehydrocostus Lactone exhibits different IC(50) values in cytotoxicity tests and has a high selectivity index .
    (Rac)-Dehydrocostus Lactone
  • HY-123059

    (rac)-ICI-118551 hydrochloride

    Adrenergic Receptor Neurological Disease
    (Rac)-ICI-118551 ((Rac)-ICI-118551) hydrochloride is a selective β2-adrenergic receptor antagonist. (Rac)-ICI-118551 hydrochloride can inhibit dendrite ramification of hippocampal neurons in a mouse model of Alzheimer's disease .
    (Rac)-Zenidolol hydrochloride
  • HY-B1205S
    (Rac)-Atropine-d3
    1 Publications Verification

    (rac)-Tropine tropate-d3; (rac)-Hyoscyamine-d3

    mAChR Endogenous Metabolite Isotope-Labeled Compounds Others
    (Rac)-Atropine-d3 is the deuterium labeled (Rac)-Atropine[1].
    (Rac)-Atropine-d3
  • HY-132352S1

    Isotope-Labeled Compounds Others
    (Rac)-4-Hydroxy Duloxetine-d3 is the deuterium labeled (Rac)-4-Hydroxy Duloxetine.
    (Rac)-4-Hydroxy Duloxetine-d3
  • HY-139573A

    (rac)-FT-4202

    Pyruvate Kinase Cardiovascular Disease
    (Rac)-Etavopivat ((Rac)-FT-4202) is an isomer of Etavopivat (HY-139573). Etavopivat is an orally active erythrocyte pyruvate kinase-R (PKR) activator that can be used in studies of sickle cell disease and other haemoglobinopathies .
    (Rac)-Etavopivat
  • HY-W654270A

    (rac)-NSC173328-d3; (rac)-5-Methyl THF calcium-d3

    Isotope-Labeled Compounds Others
    (rac)-Calcium N5-methyltetrahydrofolate-d3 ((rac)-NSC173328-d3) is a deuterium labeled (rac)-Calcium N5-methyltetrahydrofolate.
    (rac)-Calcium N5-methyltetrahydrofolate-d3
  • HY-106331A

    MK-927; (rac)-MK 417

    Carbonic Anhydrase Neurological Disease
    (Rac)-Sezolamide hydrochloride (MK-927; (Rac)-MK 417) is a carbonic anhydrase inhibitor (CAI) (Ki: 12.0 nM). (Rac)-Sezolamide hydrochloride has a topical intraocular pressure (IOP) lowering effect. (Rac)-Sezolamide hydrochloride can be used in glaucoma research .
    (Rac)-Sezolamide hydrochloride
  • HY-107370A

    (rac)-Tomoxetine hydrochloride; (rac)-LY 139603

    Serotonin Transporter Sodium Channel Metabolic Disease Cancer
    (Rac)-Atomoxetine hydrochloride ((Rac)-Tomoxetine (hydrochloride); (Rac)-LY 139603) is the racemic mixture of Atomoxetine hydrochloride (HY-17385). Atomoxetine hydrochloride is a selective noradrenaline reuptake inhibitor with Ki values of 5, 77 and 1451 nM for norepinephrine (NE), serotonin (5-HT) and dopamine (DA) transporters, respectively. Atomoxetine hydrochloride increases of DAEX and NEEX in the PFC and enhances catecholaminergic neurotransmission. Atomoxetine hydrochloride is a potent Na + channels (VGSCs) blocker. Atomoxetine hydrochloride can be used for attention-deficit hyperactivity disorder (ADHD) research .
    (Rac)-Atomoxetine hydrochloride
  • HY-N0585R

    (rac)-NCTD (Standard)

    Reference Standards Apoptosis Cancer
    (Rac)-Norcantharidin (Standard) is the analytical standard of (Rac)-Norcantharidin (HY-N0585). This product is intended for research and analytical applications. (Rac)-Norcantharidin ((Rac)-NCTD) is the racemic form of Norcantharidin. Norcantharidin is a demethylated derivative of Cantharidin (HY-N0209) and has antitumor activity .
    (Rac)-Norcantharidin (Standard)
  • HY-141411

    (rac)-MRI-1867

    Cannabinoid Receptor NO Synthase Others
    (Rac)-Zevaquenabant ((Rac)-MRI-1867, compound 6b) is a cannabinoid receptor type 1 (CB1R)/iNOS antagonist, with a Ki of 5.7 nM for CB1R. (Rac)-Zevaquenabant is potential for the research of liver fibrosis .
    (Rac)-Zevaquenabant
  • HY-N6030

    (rac)-Dencichin; (rac)-ODAP

    HIF/HIF Prolyl-Hydroxylase Others
    (Rac)-Dencichine ((Rac)-Dencichin) is the racemate of Dencichin. Dencichin is a non-protein amino acid originally extracted from Panax notoginseng, and can inhibit HIF-prolyl hydroxylase-2 (PHD-2) activity .
    (Rac)-Dencichine
  • HY-14955A

    (rac)-MB06322; (rac)-CS-917

    Others Others
    (Rac)-Managlinat dialanetil ((Rac)-MB06322) is a compound for the inhibition of type 2 diabetes that is in Phase II clinical trials and works by inhibiting gluconeogenesis.
    (Rac)-Managlinat dialanetil
  • HY-100096A

    (rac)-Emtricitabine sulfoxide; (rac)-Emtricitabine Degradant-III

    HIV Reverse Transcriptase Infection
    (Rac)-Emtricitabine S-oxide ((Rac)-Emtricitabine sulfoxide; (Rac)-Emtricitabine Degradant-III) is Emtricitabine S-oxide (HY-100096) racemic modification. Emtricitabine S-oxide is a major degradation product of Emtricitabine. Emtricitabine is a potent nucleoside reverse transcriptase inhibitor used for the treatment of HIV infection.
    (Rac)-Emtricitabine S-oxide
  • HY-104065A

    (rac)-SHR-1258

    Drug Isomer Cancer
    (Rac)-Pyrotinib ((Rac)-SHR-1258) is the racemic form of Pyrotinib (HY-104065). Pyrotinib is a potent and selective dual EGFR/HER2 receptor inhibitor.
    (Rac)-Pyrotinib
  • HY-105185B

    (rac)-SNK 860

    Aldose Reductase Metabolic Disease
    (Rac)-Fidarestat ((Rac)-SNK 860) is the racemate of Fidarestat (HY-105185). (Rac)-Fidarestat is a potent aldose reductase inhibitor .
    (Rac)-Fidarestat
  • HY-50892

    (rac)-Seliciclib; (rac)-CYC202

    CDK Apoptosis Infection Cardiovascular Disease Neurological Disease Inflammation/Immunology Cancer
    (Rac)-Roscovitine ((Rac)-Seliciclib) is a selective cyclin-dependent kinases (CDKs) inhibitor. (Rac)-Roscovitine binds to the active sites of CDKs competitively with ATP, inhibiting the phosphorylation activity of CDKs. (Rac)-Roscovitine induces apoptosis in cancer cells. (Rac)-Roscovitine is promising for research of cancers or other diseases associated with CDK dysregulation, such as neurodegenerative diseases, cardiac disorders, viral and protozoan infections, glomerulonephritis, and chronic inflammation .
    (Rac)-Roscovitine
  • HY-13728B

    (rac)-ZD 9331; (rac)-BGC9331

    Thymidylate Synthase Cancer
    (Rac)-Plevitrexed ((Rac)-ZD 9331; (Rac)-BGC9331)?is a racemate of Plevitrexed. Plevitrexed is an orally active and potent thymidylate synthase (TS) inhibitor. (Rac)-Plevitrexed is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
    (Rac)-Plevitrexed
  • HY-106964A

    5-HT Receptor Neurological Disease
    (Rac)-S 16924 is a partial agonist of the 5-HT1A receptor. (Rac)-S 16924 regulates signaling through its interaction with the 5-HT1A receptor, and (Rac)-S 16924 can stabilize the receptor in its G-protein-coupled conformation without fully activating it, which may affect intracellular signaling pathways associated with this receptor. (Rac)-S 16924 can be used to study the 5-HT1A receptor in mental disorders, especially schizophrenia .
    (Rac)-S 16924
  • HY-76570A

    (rac)-Desfesoterodine hydrochloride; (rac)-PNU-200577 hydrochloride

    mAChR Neurological Disease
    (Rac)-5-Hydroxymethyl Tolterodine ((Rac)-Desfesoterodine) hydrochloride, an active metabolite of Tolterodine, is a mAChR antagonist (Ki values of 2.3 nM, 2 nM, 2.5 nM, 2.8 nM, and 2.9 nM for M1, M2, M3, M4, and M5 receptors, respectively). (Rac)-5-Hydroxymethyl Tolterodine hydrochloride can be used for overactive bladder research .
    (Rac)-5-Hydroxymethyl Tolterodine hydrochloride
  • HY-W422288

    (rac)-Ketoconazol; (rac)-R 41400

    Fungal Cytochrome P450 Infection
    (Rac)-Ketoconazole ((Rac)-R 41400) is an antifungal imidazole compound with oral activity. (Rac)-Ketoconazole interferes with ergosterol synthesis by inhibiting cytochrome P450-dependent 14α-sterol demethylase (CYP51), a key enzyme on the fungal cell membrane, leading to membrane dysfunction and ultimately inhibition of fungal growth and reproduction. (Rac)-Ketoconazole is indicated for studies of fungal infections .
    (Rac)-Ketoconazole
  • HY-I0635

    (rac)-CC-10004

    Phosphodiesterase (PDE) Inflammation/Immunology
    (Rac)-Apremilast ((Rac)-CC-10004) is the racemic mixture of Apremilast. (Rac)-Apremilast has anti-inflammatory properties and can be used for research on inflammatory diseases, such as psoriasis .
    (Rac)-Apremilast
  • HY-114643

    (rac)-IMR-687

    Phosphodiesterase (PDE) Cardiovascular Disease
    (Rac)-Tovinontrine ((Rac)-IMR-687) is a phosphodiesterase 9 (PDE9) inhibitor that increases cyclic guanosine monophosphate (cGMP) levels. (Rac)-Tovinontrine is promising for research of thalassemia .
    (Rac)-Tovinontrine
  • HY-167933

    (rac)-SB-202026 hydrochloride; (rac)-Memric hydrochloride

    mAChR Neurological Disease
    (Rac)-Sabcomeline ((Rac)-SB-202026) hydrochloride serves as an M1 receptor agonist, making it a valuable tool for research into Alzheimer's disease.
    (Rac)-Sabcomeline hydrochloride
  • HY-14687

    (rac)-BMN-673; (rac)-LT-673

    PARP Cancer
    (rac)-Talazoparib ((rac)-BMN-673) (Compound 47) is the orally active inhibitor for PARP1/2 with Ki of 1.2 nM and 0.87 nM. (rac)-Talazoparib inhibits cellular PARylation with an EC50 of 2.51 nM. (rac)-Talazoparib causes the accumulation of DNA damage, inhibits proliferation of BRCA1/2-mutated MX-1 cell and Capan-1 cell with IC50 of 0.3 nM and 5 nM. (rac)-Talazoparib exhibits antitumor efficacy in mouse models .
    (rac)-Talazoparib
  • HY-120583

    Bacterial Infection
    (Rac)-LY 255262 is a pyrazolidinone-derivative that has antibacterial activity .
    (Rac)-LY 255262
  • HY-N16557

    Apoptosis EGFR STAT PERK Cancer
    (Rac)-8-Gingerol is a non-volatile component. (Rac)-8-Gingerol can be extracted from ginger. (Rac)-8-Gingerol enhances Apoptosis. (Rac)-8-Gingerol decreases the level of phosphorylated EGFR and, accordingly, the phosphorylation levels of its downstream effectors, STAT3 and ERK. (Rac)-8-Gingerol exhibits anticancer activity against colorectal cancer .
    (Rac)-8-Gingerol
  • HY-12693A

    (rac)-IAA-94

    Chloride Channel Others
    (Rac)-Methylindazone ((Rac)-IAA-94) is the racemate of Methylindazone. Methylindazone is a potent CLIC1 channel blocker .
    (Rac)-Methylindazone
  • HY-CE01767

    rac-Etomoxir-coenzyme A

    Biochemical Assay Reagents Metabolic Disease
    Rac-Etomoxir-CoA (Rac-Etomoxir-coenzyme A) is a coenzyme A derivative .
    Rac-Etomoxir-CoA
  • HY-124559

    (rac)-CHR-3996

    HDAC Cancer
    (Rac)-Nanatinostat ((Rac)-CHR-3996, example 44) is a potent HDAC inhibitor with an IC50 of <330 nM. (Rac)-Nanatinostat has anticancer effects and can effectively inhibit the cell growth of HeLa, U937 and HUT cells .
    (Rac)-Nanatinostat
  • HY-117173

    AGN1135; (rac)-TVP1012

    Monoamine Oxidase Neurological Disease
    (Rac)-Rasagiline (AGN1135) is the racemate of Rasagiline. (Rac)-Rasagiline is a selective type B MAO (MAO-B) inhibitor. (Rac)-Rasagiline can be used for Parkinson's disease research. (Rac)-Rasagiline protects against MPTP (HY-15608)-induced toxicity .
    (Rac)-Rasagiline
  • HY-107370AS1

    (rac)-Tomoxetine-d5 hydrochloride; (rac)-LY 139603-d5

    Isotope-Labeled Compounds Others
    (Rac)-Atomoxetine-d5 (hydrochloride) is the deuterium labeled (Rac)-Atomoxetine hydrochloride .
    (Rac)-Atomoxetine-d5 hydrochloride
  • HY-76570S2

    (rac)-Desfesoterodine-d5; (rac)-PNU-200577-d5

    mAChR Isotope-Labeled Compounds Neurological Disease
    (Rac)-5-hydroxymethyl Tolterodine-d5 ((Rac)-Desfesoterodine-d5; (Rac)-PNU-200577-d5) is deuterium-labeled (Rac)-5-Hydroxymethyl Tolterodine (HY-76570) .
    (Rac)-5-Hydroxymethyl tolterodine-d5
  • HY-117090

    (rac)-4,5-DHP-AMT

    5-HT Receptor Others
    (rac)-AL-37350A ((rac)-4,5-DHP-AMT) is a 5-HT2 receptor agonist with intraocular pressure-lowering activity. (rac)-AL-37350A has high affinity and selectivity for the 5-HT2 receptor and effectively reduces intraocular pressure in conscious hypertensive cynomolgus monkeys.
    (rac)-AL-37350A

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