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Idroxioleic acid (Synonyms: (R)-2-Hydroxyoleic acid; (R)-2-OHOA)

Cat. No.: HY-139784
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Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA), the R enantiomer of (Rac)-Idroxioleic acid, is an orally active fatty acid that modulates the lipid composition and structure of the membranes. Idroxioleic acid has antitumor activities.

For research use only. We do not sell to patients.

Idroxioleic acid Chemical Structure

Idroxioleic acid Chemical Structure

CAS No. : 182370-45-2

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Description

Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA), the R enantiomer of (Rac)-Idroxioleic acid, is an orally active fatty acid that modulates the lipid composition and structure of the membranes. Idroxioleic acid has antitumor activities[1].

In Vitro

Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA) inhibited the growth of A549, lung adenocarcinoma cell line with an IC50 of 252 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

In Vivo

Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA; 400 mg/kg; p.o.; daily; for 21 days) causes a reduction in tumor volume of about 20-25% after 21 days[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male NUDE (Swiss) Crl:NU(Ico)-Foxn1nu mice (5 weeks old, 30-35 g) injected with A549 human lung cancer cells[1]
Dosage: 400 mg/kg
Administration: p.o.; daily; for 21 days
Result: Caused a reduction in tumor volume of about 20-25% after 21 days.
Molecular Weight

298.46

Formula

C₁₈H₃₄O₃

CAS No.
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Idroxioleic acid
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