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  4. Idroxioleic acid

Idroxioleic acid  (Synonyms: NFX88; (R)-2-Hydroxyoleic acid; (R)-2-OHOA)

Cat. No.: HY-139784
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Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA), the R enantiomer of (Rac)-Idroxioleic acid, is an orally active fatty acid that modulates the lipid composition and structure of the membranes. Idroxioleic acid has antitumor activities.

For research use only. We do not sell to patients.

Idroxioleic acid Chemical Structure

Idroxioleic acid Chemical Structure

CAS No. : 182370-45-2

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Idroxioleic acid Related Antibodies

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Description

Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA), the R enantiomer of (Rac)-Idroxioleic acid, is an orally active fatty acid that modulates the lipid composition and structure of the membranes. Idroxioleic acid has antitumor activities[1].

In Vitro

Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA) inhibited the growth of A549, lung adenocarcinoma cell line with an IC50 of 252 μM[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Idroxioleic acid Related Antibodies
In Vivo

Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA; 400 mg/kg; p.o.; daily; for 21 days) causes a reduction in tumor volume of about 20-25% after 21 days[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: Male NUDE (Swiss) Crl:NU(Ico)-Foxn1nu mice (5 weeks old, 30-35 g) injected with A549 human lung cancer cells[1]
Dosage: 400 mg/kg
Administration: p.o.; daily; for 21 days
Result: Caused a reduction in tumor volume of about 20-25% after 21 days.
Clinical Trial
Molecular Weight

298.46

Formula

C18H34O3
CAS No.
SMILES

OC([C@H](O)CCCCCC/C=C\CCCCCCCC)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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Idroxioleic acid Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Idroxioleic acid182370-45-2NFX88 (R)-2-Hydroxyoleic acid (R)-2-OHOANFX 88NFX-88OthersorallyantitumorlipidcompositionmembranesInhibitorinhibitorinhibit

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