Idroxioleic acid
Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA), the R enantiomer of (Rac)-Idroxioleic acid, is an orally active fatty acid that modulates the lipid composition and structure of the membranes. Idroxioleic acid has antitumor activities.
For research use only. We do not sell to patients.
- CAS No.: 182370-45-2
- Formula: C18H34O3
- Molecular Weight:298.46
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All Endogenous Metabolite Isoforms
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Biological Activity
Idroxioleic acid ((R)-2-Hydroxyoleic acid; (R)-2-OHOA) inhibited the growth of A549, lung adenocarcinoma cell line with an IC50 of 252 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male NUDE (Swiss) Crl:NU(Ico)-Foxn1nu mice (5 weeks old, 30-35 g) injected with A549 human lung cancer cells[1]
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Dosage:400 mg/kg
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Administration:p.o.; daily; for 21 days
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Result:Caused a reduction in tumor volume of about 20-25% after 21 days.
Chemical Information
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CAS No. 182370-45-2
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Molecular Weight 298.46
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Formula C18H34O3
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SMILES
OC([C@H](O)CCCCCC/C=C\CCCCCCCC)=O
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Synonyms
(R)-2-Hydroxyoleic acid; (R)-2-OHOA; (R)-LAM561
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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