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United States

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Cat. No.: HY-157294B

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(Rac)-GSK866

(Synonyms: GSK47866A)

(Rac)-GSK866 (GSK47866A) is a non-steroidal glucocorticoid receptor (GR) ligand. The crystal structure of (Rac)-GSK866 bound to the GR LBD (3E7C) can be used as a model to study the mechanism of action of ligands of the same class.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 960248-81-1
화학식: C₂₃H₂₁Cl₂F₄N₅O₃
분자량:562.34

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

(Rac)-GSK866 Chemical Structure

CAS No.: 960248-81-1

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Chemical Information

CAS No. 960248-81-1
분자량 562.34
화학식 C₂₃H₂₁Cl₂F₄N₅O₃
SMILES

O=C(C1=C(N)N(C2=CC=C(C=C2)F)N=C1)NCC(CN(CC)C(C3=C(Cl)C=CC=C3Cl)=O)(C(F)(F)F)O
Synonyms

GSK47866A
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Trebble PJ, et al. A ligand-specific kinetic switch regulates glucocorticoid receptor trafficking and function. J Cell Sci. 2013 Jul 15;126(Pt 14):3159-69. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

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Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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