(Rac)-Vazegepant-13C,d3
(Rac)-Vazegepant-13C,d3 ((Rac)-Zavegepant-13C,d3; (Rac)-BHV-3500-13C,d3) is the deuterated, 13C-labeled Vazegepant (HY-134992). Vazegepant (Zavegepant; BHV-3500) is an orally active calcitonin gene-related peptide (CGRP) receptor antagonist with a Ki of 23 pM for human CGRP receptor and an EC50 of 880 pM for reversing CGRP-induced vasodilation in human intracranial arteries. Vazegepant can block CGRP-mediated vasodilation in the trigeminal vascular system and inhibit neuronal circuit sensitization. Vazegepant can be used in migraine-related research.
For research use only. We do not sell to patients.
- Formula: C3513CH43D3N8O3
- Molecular Weight:642.81
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled CAS 1337918-83-8
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Molecular Weight 642.81
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Formula C3513CH43D3N8O3
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SMILES
CC1=C2NN=CC2=CC(CC(NC(N3CCC(C4=CC5=CC=CC=C5NC4=O)CC3)=O)C(N6CCN(C7CCN([13C]([2H])([2H])[2H])CC7)CC6)=O)=C1
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Synonyms
(Rac)-Zavegepant-13C,d3; (Rac)-BHV-3500-13C,d3
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(Rac)-Vazegepant-13C,d3 Related Classifications
HY-134992S Related Classifications
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