1. Neuronal Signaling
  2. Serotonin Transporter
  3. (Rac)-Dapoxetine hydrochloride

(Rac)-Dapoxetine hydrochloride  (Synonyms: (Rac)-LY-210448 hydrochloride)

Cat. No.: HY-W290532 Purity: 99.49%
Handling Instructions Technical Support

(Rac)-Dapoxetine hydrochloride is a racemate of Dapoxetine hydrochloride (HY-B0304A). Dapoxetine (LY-210448) hydrochloride is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine hydrochloride can be used for the research of premature ejaculation (PE).

For research use only. We do not sell to patients.

(Rac)-Dapoxetine hydrochloride

(Rac)-Dapoxetine hydrochloride Chemical Structure

CAS No. : 1071929-03-7

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
100 mg In-stock
250 mg Get quote
1 g Get quote
5 g   Get quote  
10 g   Get quote  

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This product is a controlled substance and not for sale in your territory.

Other Forms of (Rac)-Dapoxetine hydrochloride:

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Description

(Rac)-Dapoxetine hydrochloride is a racemate of Dapoxetine hydrochloride (HY-B0304A). Dapoxetine (LY-210448) hydrochloride is an orally active and selective serotonin reuptake inhibitor (SSRI). Dapoxetine hydrochloride can be used for the research of premature ejaculation (PE)[1].

Molecular Weight

341.87

Formula

C21H24ClNO

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CN(C)C(C1=CC=CC=C1)CCOC2=CC=CC3=C2C=CC=C3.Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (146.25 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.9251 mL 14.6254 mL 29.2509 mL
5 mM 0.5850 mL 2.9251 mL 5.8502 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

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Volume (start)

V1

=
Concentration (final)

C2

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Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.9251 mL 14.6254 mL 29.2509 mL 73.1272 mL
5 mM 0.5850 mL 2.9251 mL 5.8502 mL 14.6254 mL
10 mM 0.2925 mL 1.4625 mL 2.9251 mL 7.3127 mL
15 mM 0.1950 mL 0.9750 mL 1.9501 mL 4.8751 mL
20 mM 0.1463 mL 0.7313 mL 1.4625 mL 3.6564 mL
25 mM 0.1170 mL 0.5850 mL 1.1700 mL 2.9251 mL
30 mM 0.0975 mL 0.4875 mL 0.9750 mL 2.4376 mL
40 mM 0.0731 mL 0.3656 mL 0.7313 mL 1.8282 mL
50 mM 0.0585 mL 0.2925 mL 0.5850 mL 1.4625 mL
60 mM 0.0488 mL 0.2438 mL 0.4875 mL 1.2188 mL
80 mM 0.0366 mL 0.1828 mL 0.3656 mL 0.9141 mL
100 mM 0.0293 mL 0.1463 mL 0.2925 mL 0.7313 mL
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(Rac)-Dapoxetine hydrochloride
Cat. No.:
HY-W290532
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