(Rac)-SAR131675
(Rac)-SAR131675 is the racemate of SAR131675. SAR131675 is a potent and selective VEGFR3 inhibitor with an IC50 of 23 nM.
For research use only. We do not sell to patients.
- CAS No.: 1092539-44-0
- Formula: C18H22N4O4
- Molecular Weight:358.39
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
All VEGFR Isoforms
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Biological Activity
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VEGFR3 |
Chemical Information
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CAS No. 1092539-44-0
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Appearance Solid
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Molecular Weight 358.39
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Formula C18H22N4O4
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Color White to off-white
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SMILES
O=C(C1=C(N)N(CC)C2=C(C=CC(C#CC(C)(O)COC)=N2)C1=O)NC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (267 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
[1]. Mitroshina EV, et al. Neuroprotective Effect of Kinase Inhibition in Ischemic Factor Modeling In Vitro. Int J Mol Sci. 2021;22(4):1885. [Content Brief]
[2]. Alam A, et al. SAR131675, a potent and selective VEGFR-3-TK inhibitor with antilymphangiogenic, antitumoral, and antimetastatic activities. Mol Cancer Ther. 2012 Aug;11(8):1637-49. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(Rac)-SAR131675 Related Classifications
HY-123050 Related Classifications
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