(Rac)-VU 6008667
Based on 1 Customer Validation
(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) (IC50=1.8 μM, pIC50= 5.75), has high CNS penetration.
For research use only. We do not sell to patients.
- Purity: 99.30%
- CAS No.: 2092917-63-8
- Formula: C24H17ClF2N2O2
- Molecular Weight:438.85
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Membrane Protein-targeted Compound Library
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Membrane Receptor-targeted Compound Library
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Highly Selective Inhibitors Library
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Allosteric Modulators (AMs) Compound Library
HY-L170
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Bioactive Compound Library Max
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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High-Throughput Bioactive Compound Library
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Lactylation Compound Library
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Biological Activity
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mAChR5 |
Chemical Information
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CAS No. 2092917-63-8
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Appearance Solid
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Molecular Weight 438.85
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Formula C24H17ClF2N2O2
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Color White to off-white
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SMILES
O=C1N2C(N(C(C3=CC=C(F)C(F)=C3)=O)CC2)(C4=CC=C(Cl)C(C)=C4)C5=C1C=CC=C5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 125 mg/mL (284.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2787 mL | 11.3934 mL | 22.7868 mL | 56.9671 mL |
| 5 mM | 0.4557 mL | 2.2787 mL | 4.5574 mL | 11.3934 mL | |
| 10 mM | 0.2279 mL | 1.1393 mL | 2.2787 mL | 5.6967 mL | |
| 15 mM | 0.1519 mL | 0.7596 mL | 1.5191 mL | 3.7978 mL | |
| 20 mM | 0.1139 mL | 0.5697 mL | 1.1393 mL | 2.8484 mL | |
| 25 mM | 0.0911 mL | 0.4557 mL | 0.9115 mL | 2.2787 mL | |
| 30 mM | 0.0760 mL | 0.3798 mL | 0.7596 mL | 1.8989 mL | |
| 40 mM | 0.0570 mL | 0.2848 mL | 0.5697 mL | 1.4242 mL | |
| 50 mM | 0.0456 mL | 0.2279 mL | 0.4557 mL | 1.1393 mL | |
| 60 mM | 0.0380 mL | 0.1899 mL | 0.3798 mL | 0.9495 mL | |
| 80 mM | 0.0285 mL | 0.1424 mL | 0.2848 mL | 0.7121 mL | |
| 100 mM | 0.0228 mL | 0.1139 mL | 0.2279 mL | 0.5697 mL |
(Rac)-VU 6008667 Related Classifications
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