(Rac)-VU 6008667
Based on 1 Customer Validation
(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) (IC50=1.8 μM, pIC50= 5.75), has high CNS penetration.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.30%
- CAS 番号: 2092917-63-8
- 分子式: C24H17ClF2N2O2
- 分子量:438.85
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
IC50 & Target
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mAChR5 |
化学情報
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CAS 番号 2092917-63-8
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性状 Solid
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分子量 438.85
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分子式 C24H17ClF2N2O2
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Color White to off-white
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SMILES
O=C1N2C(N(C(C3=CC=C(F)C(F)=C3)=O)CC2)(C4=CC=C(Cl)C(C)=C4)C5=C1C=CC=C5
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 125 mg/mL (284.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2787 mL | 11.3934 mL | 22.7868 mL | 56.9671 mL |
| 5 mM | 0.4557 mL | 2.2787 mL | 4.5574 mL | 11.3934 mL | |
| 10 mM | 0.2279 mL | 1.1393 mL | 2.2787 mL | 5.6967 mL | |
| 15 mM | 0.1519 mL | 0.7596 mL | 1.5191 mL | 3.7978 mL | |
| 20 mM | 0.1139 mL | 0.5697 mL | 1.1393 mL | 2.8484 mL | |
| 25 mM | 0.0911 mL | 0.4557 mL | 0.9115 mL | 2.2787 mL | |
| 30 mM | 0.0760 mL | 0.3798 mL | 0.7596 mL | 1.8989 mL | |
| 40 mM | 0.0570 mL | 0.2848 mL | 0.5697 mL | 1.4242 mL | |
| 50 mM | 0.0456 mL | 0.2279 mL | 0.4557 mL | 1.1393 mL | |
| 60 mM | 0.0380 mL | 0.1899 mL | 0.3798 mL | 0.9495 mL | |
| 80 mM | 0.0285 mL | 0.1424 mL | 0.2848 mL | 0.7121 mL | |
| 100 mM | 0.0228 mL | 0.1139 mL | 0.2279 mL | 0.5697 mL |
(Rac)-VU 6008667 関連分類
HY-101281A 関連分類
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