(Rac)-VU 6008667
Based on 1 Customer Validation
(Rac)-VU 6008667 is a selective negative allosteric modulator of muscarinic acetylcholine receptor subtype 5 (M5 NAM) (IC50=1.8 μM, pIC50= 5.75), has high CNS penetration.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté : 99.30%
- CAS No.: 2092917-63-8
- Formule: C24H17ClF2N2O2
- Masse moléculaire:438.85
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Description
IC50 & Target
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mAChR5 |
Chemical Information
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CAS No. 2092917-63-8
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Appearance Solid
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Masse moléculaire 438.85
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Formule C24H17ClF2N2O2
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Color White to off-white
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SMILES
O=C1N2C(N(C(C3=CC=C(F)C(F)=C3)=O)CC2)(C4=CC=C(Cl)C(C)=C4)C5=C1C=CC=C5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
In Vitro:
DMSO : 125 mg/mL (284.84 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2787 mL | 11.3934 mL | 22.7868 mL | 56.9671 mL |
| 5 mM | 0.4557 mL | 2.2787 mL | 4.5574 mL | 11.3934 mL | |
| 10 mM | 0.2279 mL | 1.1393 mL | 2.2787 mL | 5.6967 mL | |
| 15 mM | 0.1519 mL | 0.7596 mL | 1.5191 mL | 3.7978 mL | |
| 20 mM | 0.1139 mL | 0.5697 mL | 1.1393 mL | 2.8484 mL | |
| 25 mM | 0.0911 mL | 0.4557 mL | 0.9115 mL | 2.2787 mL | |
| 30 mM | 0.0760 mL | 0.3798 mL | 0.7596 mL | 1.8989 mL | |
| 40 mM | 0.0570 mL | 0.2848 mL | 0.5697 mL | 1.4242 mL | |
| 50 mM | 0.0456 mL | 0.2279 mL | 0.4557 mL | 1.1393 mL | |
| 60 mM | 0.0380 mL | 0.1899 mL | 0.3798 mL | 0.9495 mL | |
| 80 mM | 0.0285 mL | 0.1424 mL | 0.2848 mL | 0.7121 mL | |
| 100 mM | 0.0228 mL | 0.1139 mL | 0.2279 mL | 0.5697 mL |
(Rac)-VU 6008667 Related Classifications
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