2. Metabolic Enzyme/Protease
  3. Drug Metabolite
  4. (Rac)-EGC-M7

(Rac)-EGC-M7 is a racemic microbial metabolite of green tea Catechin (EGC) (HY-N0898), and acts as an inhibitor of nitric oxide production and cancer cell growth. (Rac)-EGC-M7 can be used in the research of esophageal squamous cell carcinoma and colon adenocarcinoma.

For research use only. We do not sell to patients.

(Rac)-EGC-M7

(Rac)-EGC-M7 Chemical Structure

CAS No. : 509078-28-8

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(Rac)-EGC-M7 Related Antibodies

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Description

(Rac)-EGC-M7 is a racemic microbial metabolite of green tea Catechin (EGC) (HY-N0898), and acts as an inhibitor of nitric oxide production and cancer cell growth. (Rac)-EGC-M7 can be used in the research of esophageal squamous cell carcinoma and colon adenocarcinoma[1].

In Vitro

(Rac)-EGC-M7 (Compound M4 (1)) (15-73 μM) potently inhibits the growth of human esophageal squamous cell carcinoma cell line (KYSE150), human colon adenocarcinoma cell lines (HT-29, HCT-116), immortalized human intestinal epithelial cell line (INT-407) and immortalized rat intestinal epithelial cell line (IEC-6), with IC50 values ranging from 15 to 73 μM[1].
(Rac)-EGC-M7 (20 μM) inhibits nitric oxide production by 50% in LPS (HY-D1056)-stimulated murine macrophage RAW264.7 cells, with no effect on arachidonic acid release[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

(Rac)-EGC-M7 Related Antibodies
Molecular Weight

224.21

Formula

C11H12O5
CAS No.
SMILES

O=C1OC(CC1)CC2=CC(O)=C(C(O)=C2)O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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(Rac)-EGC-M7 Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Rac)-EGC-M7509078-28-8Drug Metaboliteesophageal squamous cell carcinomaHCT-116lipopolysaccharide-stimulated murine macrophagescolon adenocarcinomanitric oxidearachidonic acidHT-29KYSE150immortalized human cellsmalignant human cellsInhibitorinhibitorinhibit

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