(Rac)-EGC-M7
(Rac)-EGC-M7 is a racemic microbial metabolite of green tea Catechin (EGC) (HY-N0898), and acts as an inhibitor of nitric oxide production and cancer cell growth. (Rac)-EGC-M7 can be used in the research of esophageal squamous cell carcinoma and colon adenocarcinoma.
For research use only. We do not sell to patients.
- CAS No.: 509078-28-8
- Formula: C11H12O5
- Molecular Weight:224.21
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
(Rac)-EGC-M7 (Compound M4 (1)) (15-73 μM) potently inhibits the growth of human esophageal squamous cell carcinoma cell line (KYSE150), human colon adenocarcinoma cell lines (HT-29, HCT-116), immortalized human intestinal epithelial cell line (INT-407) and immortalized rat intestinal epithelial cell line (IEC-6), with IC50 values ranging from 15 to 73 μM[1].
(Rac)-EGC-M7 (20 μM) inhibits nitric oxide production by 50% in LPS (HY-D1056)-stimulated murine macrophage RAW264.7 cells, with no effect on arachidonic acid release[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 509078-28-8
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Molecular Weight 224.21
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Formula C11H12O5
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SMILES
O=C1OC(CC1)CC2=CC(O)=C(C(O)=C2)O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)