(Rac)-Bedaquiline
(Rac)-Bedaquiline is the racemate of Bedaquiline. Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting both the c- and the ε-subunit. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis.
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- CAS No.: 654655-80-8
- 화학식: C32H31BrN2O2
- 분자량:555.50
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보관:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- 순도&문서
- References
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Help & FAQs
Biological Activity
Chemical Information
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CAS No. 654655-80-8
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분자량 555.50
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화학식 C32H31BrN2O2
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SMILES
BrC1=CC=C(N=C(OC)C(C(C(CCN(C)C)(O)C2=CC=CC3=C2C=CC=C3)C4=CC=CC=C4)=C5)C5=C1
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Synonyms
(Rac)-TMC207; (Rac)-R207910
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Please store the product under the recommended conditions in the Certificate of Analysis.
순도&문서
References
[1]. Jang JC, et al. Bedaquiline susceptibility test for totally drug-resistant tuberculosis Mycobacterium tuberculosis. J Microbiol. 2017 Jun;55(6):483-487. [Content Brief]
[2]. Sarathy JP, et al. TBAJ-876 Displays Bedaquiline-Like Mycobactericidal Potency without Retaining the Parental Drug's Uncoupler Activity. Antimicrob Agents Chemother. 2020 Jan 27;64(2):e01540-19. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(Rac)-Bedaquiline Related Classifications
HY-14881B Related Classifications
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