(Rac)-Bedaquiline-d6
Based on 1 Customer Validation
(Rac)-Bedaquiline-d6 is the deuterium labeled Bedaquiline (HY-14881). Bedaquiline (TMC207) is a diarylquinoline agent and inhibits Mycobacterium tuberculosis (Mtb) F1FO-ATP synthase through targeting of both the c- and the ε-subunit. Bedaquiline has uncoupler activity. Bedaquiline is used for the multi-agent resistant tuberculosis.
For research use only. We do not sell to patients.
- Purity: 99.0%
- CAS No.: 2517573-53-2
- Formula: C32H25D6BrN2O2
- Molecular Weight:561.54
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Purity & Documentation
- References
-
Help & FAQs
All Antibiotic Isoforms
More
Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 2517573-53-2
-
Unlabeled Cas 843663-66-1
-
Appearance Solid
-
Molecular Weight 561.54
-
Formula C32H25D6BrN2O2
-
Color White to off-white
-
SMILES
BrC1=CC=C(N=C(OC)C(C(C(C2=CC=CC3=C2C=CC=C3)(O)CCN(C([2H])([2H])[2H])C([2H])([2H])[2H])C4=CC=CC=C4)=C5)C5=C1
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 12.5 mg/mL (22.26 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
-
Data Sheet (274 KB)
-
SDS (728 KB)
- English - EN (728 KB)
- Français - FR (728 KB)
- Deutsch - DE (728 KB)
- Norwegian - NO (728 KB)
- Español - ES (728 KB)
- Swedish - SV (728 KB)
- Italian - IT (728 KB)
- Korean - KR (728 KB)
- Portuguese - PT (728 KB)
-
Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7808 mL | 8.9041 mL | 17.8082 mL | 44.5204 mL |
| 5 mM | 0.3562 mL | 1.7808 mL | 3.5616 mL | 8.9041 mL | |
| 10 mM | 0.1781 mL | 0.8904 mL | 1.7808 mL | 4.4520 mL | |
| 15 mM | 0.1187 mL | 0.5936 mL | 1.1872 mL | 2.9680 mL | |
| 20 mM | 0.0890 mL | 0.4452 mL | 0.8904 mL | 2.2260 mL |
(Rac)-Bedaquiline-d6 Related Classifications
HY-14881S1 Related Classifications
Powered by Bioz