(Rac)-Finerenone-d5
(Rac)-Finerenone-d5 ((Rac)-BAY 94-8862-d5) is the deuterium labeled (Rac)-Finerenone (HY-111372A). (Rac)-Finerenone ((Rac)-BAY 94-8862) is the racemate of Finerenone. Finerenone is a third-generation, selective, and orally available nonsteroidal mineralocorticoid receptor (MR) antagonist (IC50=18 nM). Finerenone displays excellent selectivity versus glucocorticoid receptor (GR), androgen receptor (AR), and progesterone receptor (>500-fold).
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- CAS. Nr.: 2917530-31-3
- Formel: C21H17D5N4O3
- Molecular Weight:383.46
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 2917530-31-3
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Unlabeled Cas 1050477-27-4
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Molecular Weight 383.46
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Formel C21H17D5N4O3
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SMILES
[2H]C([2H])([2H])C([2H])([2H])OC1=C2C(C3=C(C=C(C=C3)C#N)OC)C(C(N)=O)=C(NC2=C(C=N1)C)C
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Synonyms
(Rac)-BAY 94-8862-d5
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)