1. Others Epigenetics Stem Cell/Wnt Protein Tyrosine Kinase/RTK JAK/STAT Signaling
  2. Isotope-Labeled Compounds JAK
  3. (Rac)-Ruxolitinib-d9

(Rac)-Ruxolitinib-d9  (Synonyms: (Rac)-INCB18424-d9; Ruxotinib racemate-d9)

Cat. No.: HY-W062703S
Handling Instructions

(Rac)-Ruxolitinib D9 ((Rac)-INCB18424 D9) is the deuterium labeled (Rac)-Ruxolitinib. (Rac)-Ruxolitinib is a JAK2 inhibitor.

For research use only. We do not sell to patients.

(Rac)-Ruxolitinib-d<sub>9</sub> Chemical Structure

(Rac)-Ruxolitinib-d9 Chemical Structure

CAS No. : 2469553-67-9

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Based on 1 publication(s) in Google Scholar

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Description

(Rac)-Ruxolitinib D9 ((Rac)-INCB18424 D9) is the deuterium labeled (Rac)-Ruxolitinib. (Rac)-Ruxolitinib is a JAK2 inhibitor[1].

In Vitro

Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

315.42

Formula

C17H9D9N6

CAS No.
SMILES

N#CCC(C1([2H])C([2H])([2H])C([2H])([2H])C([2H])([2H])C1([2H])[2H])N2C=C(C=N2)C3=C4C(NC=C4)=NC=N3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
(Rac)-Ruxolitinib-d9
Cat. No.:
HY-W062703S
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