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Cat. No.: HY-14247AR

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Fadrozole (Standard)

(Synonyms: CGS 16949A free base (Standard); (Rac)-FAD286 (Standard))

Fadrozole (Standard) is the analytical standard of Fadrozole. This product is intended for research and analytical applications. Fadrozole (CGS 16949A free base) is a potent, selective and nonsteroidal inhibitor of aromatase with an IC50 of 6.4 nM.

For research use only. We do not sell to patients.

CAS No.: 102676-47-1
Formula: C₁₄H₁₃N₃
Molecular Weight:223.28

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Fadrozole (Standard) Chemical Structure

CAS No.: 102676-47-1

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Product Information
- Information
- Application
Chemical Information
Purity & Documentation
Calculators
Help & FAQs
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Product Information

Information

Application

The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.

Chemical Information

CAS No. 102676-47-1
Molecular Weight 223.28
Formula C₁₄H₁₃N₃
SMILES

N#CC1=CC=C(C2CCCC3=CN=CN23)C=C1
Synonyms

CGS 16949A free base (Standard); (Rac)-FAD286 (Standard)
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

References

[1]. Browne LJ, et al. Fadrozole hydrochloride: a potent, selective, nonsteroidal inhibitor of aromatase for the treatment of estrogen-dependent disease. J Med Chem. 1991 Feb;34(2):725-36. [Content Brief]

[2]. Gunson DE, et al. Prevention of spontaneous tumours in female rats by fadrozole hydrochloride, an aromatase inhibitor. Br J Cancer. 1995 Jul;72(1):72-5. [Content Brief]

[3]. Morales-Montor J, et al. Inhibition of p-450 aromatase prevents feminisation and induces protection during cysticercosis. Int J Parasitol. 2002 Oct;32(11):1379-87. [Content Brief]

Calculators

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Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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