(Rac)-DNDI-8219
(Rac)-DNDI-8219 is an antituberculosis compound with potent anti-leishmanial activity. (Rac)-DNDI-8219 demonstrated superior efficacy in the Leishmania donovani mouse model. (Rac)-DNDI-8219 showed promising activity in the Leishmania infantum hamster model. (Rac)-DNDI-8219 candidate compound R-6 provided excellent oral efficacy in the same hamster model.
For research use only. We do not sell to patients.
- CAS No.: 1333170-15-2
- Formula: C13H10F3N3O5
- Molecular Weight:345.23
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MRC5 | IC50 |
>64 μM
Compound: 6
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Cytotoxicity against human MRC5 cells after 72 hrs by resazurin dye based assay
Cytotoxicity against human MRC5 cells after 72 hrs by resazurin dye based assay
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[PMID: 29461823] |
Chemical Information
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CAS No. 1333170-15-2
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Molecular Weight 345.23
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Formula C13H10F3N3O5
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SMILES
FC(F)(F)OC1=CC=C(OC2CN3C(OC2)=NC([N+]([O-])=O)=C3)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(Rac)-DNDI-8219 Related Classifications
HY-129819 Related Classifications
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