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Cat. No.: HY-106331A

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(Rac)-Sezolamide hydrochloride

(Synonyms: MK-927; (Rac)-MK 417)

(Rac)-Sezolamide hydrochloride (MK-927; (Rac)-MK 417) is a carbonic anhydrase inhibitor (CAI) (K_i: 12.0 nM). (Rac)-Sezolamide hydrochloride has a topical intraocular pressure (IOP) lowering effect. (Rac)-Sezolamide hydrochloride can be used in glaucoma research.

For research use only. We do not sell to patients.

CAS No.: 126453-94-9
Formula: C₁₁H₁₉ClN₂O₄S₃
Molecular Weight:374.93

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

(Rac)-Sezolamide hydrochloride Chemical Structure

CAS No.: 126453-94-9

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

All Carbonic Anhydrase Isoforms :

Chemical Information

CAS No. 126453-94-9
Molecular Weight 374.93
Formula C₁₁H₁₉ClN₂O₄S₃
SMILES

O=S(N)(C1=CC(C(CCS2(=O)=O)NCC(C)C)=C2S1)=O.Cl
Synonyms

MK-927; (Rac)-MK 417
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Sugrue MF, et al. MK-927: a topically active ocular hypotensive carbonic anhydrase inhibitor. J Ocul Pharmacol. 1990 Spring;6(1):9-22. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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References

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(Rac)-Sezolamide hydrochloride

All Carbonic Anhydrase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

(Rac)-Sezolamide hydrochloride Related Classifications

HY-106331A Related Classifications