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Cat. No.: HY-106332A

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Sezolamide hydrochloride

(Synonyms: MK 417; (S)-MK-927)

Sezolamide hydrochloride (MK 417) is a potent topical carbonic anhydrase inhibitor. Sezolamide hydrochloride can be used in studies to reduce intraocular pressure.

For research use only. We do not sell to patients.

CAS No.: 119271-78-2
Formula: C₁₁H₁₉ClN₂O₄S₃
Molecular Weight:374.93

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Sezolamide hydrochloride Chemical Structure

CAS No.: 119271-78-2

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Fluorescent Dye

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Biological Activity

Description

Sezolamide hydrochloride (MK 417) is a potent topical carbonic anhydrase inhibitor. Sezolamide hydrochloride can be used in studies to reduce intraocular pressure^[1].

All Carbonic Anhydrase Isoforms :

Chemical Information

CAS No. 119271-78-2
Molecular Weight 374.93
Formula C₁₁H₁₉ClN₂O₄S₃
SMILES

O=S1(C2=C(C=C(S(N)(=O)=O)S2)[C@@H](NCC(C)C)CC1)=O.Cl
Synonyms

MK 417; (S)-MK-927
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Gunning FP, et al. Two topical carbonic anhydrase inhibitors sezolamide and dorzolamide in Gelrite vehicle: a multiple-dose efficacy study. Graefes Arch Clin Exp Ophthalmol. 1993 Jul;231(7):384-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
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References

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Sezolamide hydrochloride

All Carbonic Anhydrase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Sezolamide hydrochloride Related Classifications

HY-106332A Related Classifications