2. NF-κB
  3. NF-κB
  4. (Rac)-Myrislignan

(Rac)-Myrislignan is the racemate of Myrislignan. Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan attenuates LPS-induced inflammation reaction in murine macrophage cells through inhibition of NF-kB signalling pathway activation.

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(Rac)-Myrislignan Chemical Structure

(Rac)-Myrislignan Chemical Structure

CAS No. : 41535-95-9

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5 mg USD 857 In-stock
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Based on 1 publication(s) in Google Scholar

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(Rac)-Myrislignan Related Antibodies

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Description

(Rac)-Myrislignan is the racemate of Myrislignan. Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan attenuates LPS-induced inflammation reaction in murine macrophage cells through inhibition of NF-kB signalling pathway activation[1].

Molecular Weight

374.43

Formula

C21H26O6
CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC(C1=CC(OC)=C(O)C=C1)C(C)OC2=C(C=C(CC=C)C=C2OC)OC
Structure Classification
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, protect from light

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (267.07 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.6707 mL 13.3536 mL 26.7073 mL
5 mM 0.5341 mL 2.6707 mL 5.3415 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

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Purity & Documentation

Purity: ≥99.0%

COA (246 KB)

Handling Instructions (2659 KB)
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.6707 mL 13.3536 mL 26.7073 mL 66.7682 mL
5 mM 0.5341 mL 2.6707 mL 5.3415 mL 13.3536 mL
10 mM 0.2671 mL 1.3354 mL 2.6707 mL 6.6768 mL
15 mM 0.1780 mL 0.8902 mL 1.7805 mL 4.4512 mL
20 mM 0.1335 mL 0.6677 mL 1.3354 mL 3.3384 mL
25 mM 0.1068 mL 0.5341 mL 1.0683 mL 2.6707 mL
30 mM 0.0890 mL 0.4451 mL 0.8902 mL 2.2256 mL
40 mM 0.0668 mL 0.3338 mL 0.6677 mL 1.6692 mL
50 mM 0.0534 mL 0.2671 mL 0.5341 mL 1.3354 mL
60 mM 0.0445 mL 0.2226 mL 0.4451 mL 1.1128 mL
80 mM 0.0334 mL 0.1669 mL 0.3338 mL 0.8346 mL
100 mM 0.0267 mL 0.1335 mL 0.2671 mL 0.6677 mL
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(Rac)-Myrislignan Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

(Rac)-Myrislignan41535-95-9NF-κBNuclear factor-κBNuclear factor-kappaBInhibitorinhibitorinhibit

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