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(Rac)-LM11A-31 dihydrochloride 

Cat. No.: HY-110155A Purity: >98.0%
Handling Instructions

(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a non-peptide p75NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist.

For research use only. We do not sell to patients.

(Rac)-LM11A-31 dihydrochloride Chemical Structure

(Rac)-LM11A-31 dihydrochloride Chemical Structure

CAS No. : 1214672-15-7

Size Price Stock Quantity
10 mM * 1  mL in Water USD 55 In-stock
Estimated Time of Arrival: December 31
5 mg USD 50 In-stock
Estimated Time of Arrival: December 31
10 mg USD 74 In-stock
Estimated Time of Arrival: December 31
50 mg   Get quote  
100 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

Other Forms of (Rac)-LM11A-31 dihydrochloride:

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Description

(Rac)-LM11A-31 dihydrochloride is an isomer of LM11A-31 dihydrochloride. LM11A-31 dihydrochloride, a non-peptide p75NTR (neurotrophin receptor p75) modulator, is an orally active and potent proNGF (nerve growth factor) antagonist[1].

Molecular Weight

316.27

Formula

C₁₂H₂₇Cl₂N₃O₂

CAS No.

1214672-15-7

SMILES

CCC(C)C(N)C(NCCN1CCOCC1)=O.[H]Cl.[H]Cl

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, stored under nitrogen, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen, away from moisture)

Solvent & Solubility
In Vitro: 

H2O : ≥ 200 mg/mL (632.37 mM)

Ethanol : 100 mg/mL (316.19 mM; Need ultrasonic)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1619 mL 15.8093 mL 31.6186 mL
5 mM 0.6324 mL 3.1619 mL 6.3237 mL
10 mM 0.3162 mL 1.5809 mL 3.1619 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  10% EtOH    40% PEG300    5% Tween-80    45% saline

    Solubility: ≥ 2.5 mg/mL (7.90 mM); Clear solution

  • 2.

    Add each solvent one by one:  10% EtOH    90% (20% SBE-β-CD in saline)

    Solubility: ≥ 2.5 mg/mL (7.90 mM); Clear solution

  • 3.

    Add each solvent one by one:  10% EtOH    90% corn oil

    Solubility: ≥ 2.5 mg/mL (7.90 mM); Clear solution

*All of the co-solvents are provided by MCE.
References
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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Keywords:

(Rac)-LM11A-31Othersp75NTRneurotrophinreceptorp75LigandproNGFnervegrowthfactorblood-brainbarriercholinergicneuritedystrophyAlzheimer'sdiseaseInhibitorinhibitorinhibit

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Product Name:
(Rac)-LM11A-31 dihydrochloride
Cat. No.:
HY-110155A
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