country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-119361

Copy Link Print Information

(Rac)-Deox B 7,4

Name: (Rac)-Deox B 7,4
Brand: MedChemExpress
SKU: HY-119361
Availability: PreOrder

(Synonyms: (Rac)-Deoxysappanone B 7,4' dimethyl ether)

(Rac)-Deox B 7,4, a homoisoflavanoid compound, inhibits microtubule polymerization via binding near the colchicine site and promote reversible G2 arrest. (Rac)-Deox B 7,4 possesses nanomolar anti-leukemic activity.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

CAS No.: 674786-37-9
화학식: C₁₈H₁₈O₅
분자량:314.33

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

(Rac)-Deox B 7,4 Chemical Structure

CAS No.: 674786-37-9

사이즈

가격

재고

수량

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- Cellular Effect
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

Cellular Effect

Cell Line	Type	Value	Description	References
BT-549	IC₅₀	30.6 μM Compound: 3o	Cytotoxicity against human BT549 cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against human BT549 cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 29074256]
HeLa	IC₅₀	50.12 μM Compound: 3o	Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 29074256]
Vero	IC₅₀	>200 μM Compound: 3o	Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 24 hrs by MTT assay Cytotoxicity against African green monkey Vero cells assessed as reduction in cell viability after 24 hrs by MTT assay	[PMID: 29074256]

In Vitro

(Rac)-Deox B 7,4 reduces the growth and viability of all tested AML cell lines with a submicromolar IC₅₀ (range 324-556 nM)^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 674786-37-9
분자량 314.33
화학식 C₁₈H₁₈O₅
SMILES

O=C1C(COC2=C1C=CC(OC)=C2)CC3=CC=C(C(O)=C3)OC
Synonyms

(Rac)-Deoxysappanone B 7,4' dimethyl ether
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Dannie Bernard, et al. Select microtubule inhibitors increase lysosome acidity and promote lysosomal disruption in acute myeloid leukemia (AML) cells. Apoptosis. 2015 Jul;20(7):948-59. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

견적 받기 해외재고보유

Other size

견적 받기