(Rac)-Aurora A/PKC-IN-1
(Rac)-Aurora A/PKC-IN-1 (Compund 2e) is an orally active Aurora A and PKC (α, β1, β2 and θ) kinase inhibitor. (Rac)-Aurora A/PKC-IN-1 has antiproliferative activity in breast cancer cells in vitro and antimetastatic activity in vivo.
For research use only. We do not sell to patients.
- CAS No.: 2143100-98-3
- Formula: C16H14N6OSe2
- Molecular Weight:464.24
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Aurora Kinase Isoforms
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Biological Activity
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Aurora A 6.9 nM (IC50) |
PKCα 16.9 nM (IC50) |
PKCβI 12.1 nM (IC50) |
PKCβII 11.3 nM (IC50) |
PKCθ 4.2 nM (IC50) |
Chemical Information
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CAS No. 2143100-98-3
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Molecular Weight 464.24
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Formula C16H14N6OSe2
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SMILES
O=C1C2=C([Se]N1C3=NC4=C(C(NC5C[Se]CC5)=N3)NC=N4)C=CC=C2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)