2143100-98-3
2143100-98-3
Chemical Structure
(Rac)-Aurora A/PKC-IN-1
- CAS No.: 2143100-98-3
- Formula:C16H14N6OSe2
- Molecular Weight:464.24
InChIKey: JKTIMGKTTJTCFS-UHFFFAOYSA-N
SMILES: O=C1C2=C([Se]N1C3=NC4=C(C(NC5C[Se]CC5)=N3)NC=N4)C=CC=C2
Biological Activity: (Rac)-Aurora A/PKC-IN-1 (Compund 2e) is an orally active Aurora A and PKC (α, β1, β2 and θ) kinase inhibitor. (Rac)-Aurora A/PKC-IN-1 has antiproliferative activity in breast cancer cells in vitro and antimetastatic activity in vivo[1].
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(Rac)-Aurora A/PKC-IN-1 | (Rac)-Aurora A/PKC-IN-1 (Compund 2e) is an orally active Aurora A and PKC (α, β1, β2 and θ) kinase inhibitor. (Rac)-Aurora A/PKC-IN-1 has antiproliferative activity in breast cancer cells in vitro and antimetastatic activity in vivo. | |||||||||||||||||||||
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