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  3. 1,2-Dilaurin

1,2-Dilaurin  (Synonyms: (Rac)-1,2-Didodecanoylglycerol)

Cat. No.: HY-W127391 Purity: ≥98.0%
COA Handling Instructions

1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).

For research use only. We do not sell to patients.

1,2-Dilaurin Chemical Structure

1,2-Dilaurin Chemical Structure

CAS No. : 17598-94-6

Size Price Stock Quantity
5 mg USD 105 In-stock
10 mg USD 170 In-stock
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Based on 1 publication(s) in Google Scholar

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Description

1,2-Dilaurin is a diacylglycerol containing lauric acid at the sn-1 and sn-2 positions. It has been used as an internal standard for the quantification of diglycerides in rat desheathed sciatic nerves. [1] Monomolecular films containing 1,2-dilauroyl-rac-glycerol have been used as substrates to measure surface pressure and the effect of pancreatic procolipase and colipase on porcine pancreatic lipase activity. [2] References: [1]. Zhu, X. and Eichberg, J. 1,2-Diacylglycerol content and its arachidonyl-containing molecular species are reduced in the sciatic nerve of streptozotocin-induced diabetic rats. J. Neurochemistry. 55(3), 1087-1090 (1990).[2]. Wieloch, T., Borgstr m, B., Piéroni, G. et al. Porcine trypsinogen and its trypsin-activated form: lipid binding and lipase activation on monomolecular membranes. FEBS Express. 128(2), 217-220 (1981).

Molecular Weight

456.70

Formula

C27H52O5

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OCC(OC(CCCCCCCCCCC)=O)COC(CCCCCCCCCCC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 50 mg/mL (109.48 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1896 mL 10.9481 mL 21.8962 mL
5 mM 0.4379 mL 2.1896 mL 4.3792 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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Volume (start)

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C2

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V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 2.1896 mL 10.9481 mL 21.8962 mL 54.7405 mL
5 mM 0.4379 mL 2.1896 mL 4.3792 mL 10.9481 mL
10 mM 0.2190 mL 1.0948 mL 2.1896 mL 5.4741 mL
15 mM 0.1460 mL 0.7299 mL 1.4597 mL 3.6494 mL
20 mM 0.1095 mL 0.5474 mL 1.0948 mL 2.7370 mL
25 mM 0.0876 mL 0.4379 mL 0.8758 mL 2.1896 mL
30 mM 0.0730 mL 0.3649 mL 0.7299 mL 1.8247 mL
40 mM 0.0547 mL 0.2737 mL 0.5474 mL 1.3685 mL
50 mM 0.0438 mL 0.2190 mL 0.4379 mL 1.0948 mL
60 mM 0.0365 mL 0.1825 mL 0.3649 mL 0.9123 mL
80 mM 0.0274 mL 0.1369 mL 0.2737 mL 0.6843 mL
100 mM 0.0219 mL 0.1095 mL 0.2190 mL 0.5474 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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